Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KRAS | P01116 | 2/20 | 0.38 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341509 | 0.92 | TUBB1 (0.48) | TUBB1PTGS2ABCG2MAPTLMNA | |
| SCHEMBL9341498 | 0.89 | TUBB1 (0.47) | TUBB1PTGS2ABCG2LMNASMN1; SMN2 | |
| SCHEMBL9337757 | 0.89 | SMN1; SMN2 (0.42) | TUBB1PTGS2ABCG2LMNASMN1; SMN2 | |
| SCHEMBL9338012 | 0.86 | TUBB1 (0.65) | TUBB1ABCG2MAPTLMNASMN1; SMN2 | |
| SCHEMBL9341976 | 0.84 | TUBB1 (0.48) | TUBB1PTGS2ABCG2MAPTLMNA | |
| SCHEMBL9338444 | 0.84 | ABCG2 (0.56) | TUBB1PTGS2ABCG2SMN1; SMN2 | |
| SCHEMBL9338183 | 0.83 | ABCG2 (0.54) | TUBB1ABCG2MAPTSMN1; SMN2KMT2A | |
| SCHEMBL9338109 | 0.82 | ABCG2 (0.55) | TUBB1ABCG2MAPTLMNASMN1; SMN2 | |
| SCHEMBL9337997 | 0.82 | TUBB1 (0.46) | TUBB1PTGS2ABCG2MAPTLMNA | |
| SCHEMBL9338511 | 0.80 | ABCG2 (0.57) | TUBB1ABCG2MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |