Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342647 | 0.89 | TUBB1 (0.54) | SMN1; SMN2TUBB1ALDH1A1TDP1LMNA | |
| SCHEMBL9341509 | 0.86 | TUBB1 (0.48) | SMN1; SMN2TUBB1ALDH1A1LMNAABCG2 | |
| SCHEMBL9341498 | 0.86 | TUBB1 (0.47) | SMN1; SMN2TUBB1MAOBALDH1A1LMNA | |
| SCHEMBL9338183 | 0.82 | ABCG2 (0.54) | SMN1; SMN2TUBB1NPC1RAB9AABCG2 | |
| SCHEMBL9341976 | 0.81 | TUBB1 (0.48) | SMN1; SMN2TUBB1ALDH1A1LMNAABCG2 | |
| SCHEMBL9338444 | 0.80 | ABCG2 (0.56) | SMN1; SMN2TUBB1ABCG2PTGS2MAOA | |
| SCHEMBL9338012 | 0.80 | TUBB1 (0.65) | SMN1; SMN2TUBB1ALDH1A1LMNAABCG2 | |
| SCHEMBL9338511 | 0.79 | ABCG2 (0.57) | SMN1; SMN2TUBB1LMNAPOLBNPC1 | |
| SCHEMBL9342171 | 0.78 | NFE2L2 (0.56) | SMN1; SMN2MAOBALDH1A1TDP1LMNA | |
| SCHEMBL9342014 | 0.77 | MAOB (0.51) | SMN1; SMN2TUBB1MAOBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328668-B1 | NONLINEAR OPTICAL MATERIAL | NIPPON OILS & FATS CO LTD (JP) | 1994-05-25 | — | — | EP | disclosed |
| US-5045239-A | Chalcone derivative | NIPPON OIL AND FATS CO., LTD. (JP) | 1991-09-03 | — | — | US | disclosed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |