Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 19/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Vapiprost SCHEMBL8895507 | 1.00 | TBXA2R (1.00) | TBXA2RMEN1KMT2ATBXAS1 | |
| Vapiprost SCHEMBL28550 | 1.00 | TBXA2R (1.00) | TBXA2RMEN1KMT2ATBXAS1 | |
| Vapiprost SCHEMBL9342604 | 1.00 | TBXA2R (1.00) | TBXA2RMEN1KMT2ATBXAS1 | |
| Vapiprost SCHEMBL28551 | 1.00 | TBXA2R (1.00) | TBXA2RMEN1KMT2ATBXAS1 | |
| Vapiprost SCHEMBL9342608 | 1.00 | TBXA2R (1.00) | TBXA2RMEN1KMT2ATBXAS1 | |
| Vapiprost SCHEMBL635146 | 0.99 | TBXA2R (0.98) | TBXA2RMEN1KMT2ATBXAS1 | |
| Vapiprost SCHEMBL635147 | 0.99 | TBXA2R (0.98) | TBXA2RMEN1KMT2ATBXAS1 | |
| Vapiprost SCHEMBL27984405 | 0.99 | TBXA2R (0.98) | TBXA2RMEN1KMT2ATBXAS1 | |
| Vapiprost SCHEMBL7833619 | 0.98 | TBXA2R (0.96) | TBXA2RMEN1KMT2ATBXAS1 | |
| SCHEMBL10489337 | 0.94 | TBXA2R (0.90) | TBXA2RMEN1KMT2ATBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0234737-B1 | Preparation of piperidinylcyclopentylheptenoic acid derivatives | GLAXO GROUP LTD (GB) | 1994-07-27 | — | — | EP | disclosed |
| US-5164503-A | Reduction, hydrolysis | GLAXO GROUP LIMITED (GB) | 1992-11-17 | — | — | US | disclosed |
| US-4835278-A | Preparation of piperidinylcyclopentylheptenoic acid derivatives | GLAXO GROUP LIMITED (GB) | 1989-05-30 | — | — | US | disclosed |
| US-4530925-A | Aminocyclopentane esters and pharmaceutical formulations | GLAXO GROUP LIMITED (GB) | 1985-07-23 | — | — | US | disclosed |
| US-4410521-A | ANTICOAGULANTS, BRONCHODILATOR AGENTS | GLAXO GROUP LIMITED (GB) | 1983-10-18 | — | — | US | disclosed |
| EP-0074861-A1 | Aminocyclopentane esters and their preparation and pharmaceutical formulation | GLAXO GROUP LIMITED (GB) | 1983-03-23 | — | — | EP | disclosed |
| US-4342756-A | AS ANTITHROMBOTIC AGENTS AND ANTIASTHMATIC AGENTS | GLAXO GROUP LIMITED (GB) | 1982-08-03 | — | — | US | disclosed |