Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.70 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.70 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.70 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.70 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.70 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.65 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.65 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.65 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3641862 | 0.91 | HDAC3 (0.65) | HPGDHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL19370155 | 0.86 | CNR2 (0.74) | HPGDALDH1A1EPHX2TRPV1CNR1 | |
| SCHEMBL34461910 | 0.85 | HDAC3 (0.70) | HPGDHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL29549114 | 0.85 | HDAC6 (0.70) | HPGDHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL6645974 | 0.85 | HPGD (0.57) | HPGDHDAC3HDAC1HDAC2HDAC10 | |
| Get-73 SCHEMBL2909880 | 0.84 | HDAC3 (0.65) | HPGDHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL934145 | 0.84 | HDAC3 (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL14816841 | 0.83 | HPGD (1.00) | HPGDHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL26749658 | 0.82 | HPGD (0.76) | HPGDHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL27841358 | 0.81 | HTT (0.69) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |