Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | LSS | P48449 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.56 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30794012 | 0.87 | MAOB (0.61) | PPARGPPARAALDH1A1TP53MAPK14 | |
| SCHEMBL3641862 | 0.87 | HDAC3 (0.65) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL12993441 | 0.84 | EPHX2 (0.59) | HDAC3HDAC8HDAC6EPHX2NPC1 | |
| SCHEMBL934422 | 0.84 | HPGD (0.70) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL13361545 | 0.83 | LTA4H (0.58) | HDAC1HDAC8EPHX2 | |
| SCHEMBL10594986 | 0.83 | HDAC3 (0.60) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL2629356 | 0.82 | LSS (0.59) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL23135789 | 0.82 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL31023531 | 0.82 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL24575984 | 0.82 | MTOR (0.69) | HDAC3HDAC1HDAC2HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118561801-A | Benzo [ d ] [1,3] dioxoles compound, preparation method and application thereof | 上海医药集团股份有限公司 | 2024-08-30 | — | — | CN | disclosed |
| US-11358936-B2 | Lysyl oxidase-like 2 inhibitors and uses thereof | PHARMAKEA, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210171465-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | PHARMAKEA INC (US) | 2021-06-10 | — | — | US | disclosed |
| US-8809280-B2 | Therapeutic peptides | LYTIX BIOPHARMA AS (NO) | 2014-08-19 | — | — | US | disclosed |
| US-20130035296-A1 | THERAPEUTIC PEPTIDES | LYTIX BIOPHARMA AS (NO) | 2013-02-07 | — | — | US | disclosed |
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |
| US-5698552-A | EXHIBIT PLATELET ACTIVATING FACTOR-ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM KG (DE) | 1997-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035296-A1 | THERAPEUTIC PEPTIDES | VIP, LNPEP, ANPEP | HDAC3 3627/4885HDAC1 3756/4885HDAC2 3686/4885 |
| US-11358936-B2 | Lysyl oxidase-like 2 inhibitors and uses thereof | LOXL2, LOXL1, LOX | HDAC3 1783/4885HDAC1 1020/4885HDAC2 698/4885 |
| US-20210171465-A1 | LYSYL OXIDASE-LIKE 2 INHIBITORS AND USES THEREOF | LOXL2, LOXL1, LOX | HDAC3 1783/4885HDAC1 1020/4885HDAC2 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.