Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 4/20 | 0.51 |
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25138775 | 0.98 | HDAC1 (0.59) | HDAC1HDAC8PTPN2PTPN1PTPN6 | |
| SCHEMBL934147 | 0.93 | HDAC1 (0.57) | HDAC1HDAC8PTPN2PTPN1PTPN6 | |
| Hydrochloric Acid SCHEMBL30882461 | 0.91 | HDAC1 (0.55) | HDAC1HDAC8PTPN2PTPN1PTPN6 | |
| SCHEMBL2316007 | 0.87 | TAAR1 (0.57) | HDAC1HDAC8TAAR1CES1FFAR1 | |
| SCHEMBL14188237 | 0.86 | HDAC1 (0.67) | HDAC1HDAC8PTPN2PTPN1PTPN6 | |
| SCHEMBL25172817 | 0.86 | MAPT (0.62) | HDAC1HDAC8FAAHCES1HDAC3 | |
| SCHEMBL23176837 | 0.86 | MAPT (0.62) | HDAC1HDAC8FAAHCES1HDAC3 | |
| SCHEMBL3809501 | 0.85 | MAPT (0.57) | HDAC1HDAC8FAAHCES1HDAC3 | |
| SCHEMBL675019 | 0.85 | MAPT (0.57) | HDAC1HDAC8FAAHCES1HDAC3 | |
| SCHEMBL11638365 | 0.85 | HDAC1 (0.56) | HDAC1HDAC8PTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |