Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30882461 | 0.98 | HDAC1 (0.55) | HDAC1HDAC8TAAR1PTPN2PTPN1 | |
| SCHEMBL25138775 | 0.95 | HDAC1 (0.59) | HDAC1HDAC8TAAR1PTPN2PTPN1 | |
| SCHEMBL934424 | 0.93 | HDAC1 (0.58) | HDAC1HDAC8TAAR1PTPN2PTPN1 | |
| SCHEMBL2316007 | 0.91 | TAAR1 (0.57) | HDAC1HDAC8TAAR1FFAR1MAOB | |
| SCHEMBL14188237 | 0.86 | HDAC1 (0.67) | HDAC1HDAC8TAAR1PTPN2PTPN1 | |
| SCHEMBL3634320 | 0.86 | MAOB (0.59) | HDAC1HDAC8TAAR1FFAR1MAOB | |
| SCHEMBL1454387 | 0.85 | FFAR1 (0.60) | HDAC1HDAC8TAAR1FFAR1PDPK1 | |
| Hydrochloric Acid SCHEMBL2763476 | 0.84 | FFAR1 (0.59) | HDAC1HDAC8TAAR1FFAR1PDPK1 | |
| SCHEMBL5182649 | 0.84 | HDAC1 (0.55) | HDAC1HDAC8TAAR1PTPN2PTPN1 | |
| SCHEMBL27458184 | 0.84 | NR1H4 (0.44) | HDAC1HDAC8PTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1780821-A | Heterocyclic kinase inhibitors. | ABBOTT LAB (US) | 2006-05-31 | — | — | CN | claimed |
| EP-1073633-A2 | SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 | ABBOTT LABORATORIES (US) | 2001-02-07 | — | — | EP | claimed |
| WO-1999057098-A2 | SUBSTITUTED BETA-AMINO ACID INHIBITORS OF METHIONINE AMINOPEPTIDASE-2 | ABBOTT LABORATORIES (US) | 1999-11-11 | — | — | WO | claimed |
| US-8809280-B2 | Therapeutic peptides | LYTIX BIOPHARMA AS (NO) | 2014-08-19 | — | — | US | disclosed |
| US-20130035296-A1 | THERAPEUTIC PEPTIDES | LYTIX BIOPHARMA AS (NO) | 2013-02-07 | — | — | US | disclosed |
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |
| CN-1780821-A | Heterocyclic kinase inhibitors. | ABBOTT LAB (US) | 2006-05-31 | — | — | CN | disclosed |
| US-5698552-A | EXHIBIT PLATELET ACTIVATING FACTOR-ANTAGONISTIC ACTIVITY | BOEHRINGER INGELHEIM KG (DE) | 1997-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035296-A1 | THERAPEUTIC PEPTIDES | VIP, LNPEP, ANPEP | HDAC1 3756/4885HDAC8 3871/4885TAAR1 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.