SCHEMBL9344622

SCHEMBL9344622

C=CCCCCC1(CCCCC=C)CC[Si](C)(C)[Si](C)(C)O1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1241878 0.98 TSHR (0.33) TSHR
SCHEMBL1243011 0.98 TSHR (0.33) TSHR
SCHEMBL1242579 0.95
SCHEMBL1241844 0.88
SCHEMBL335921 0.79
SCHEMBL4558022 0.78
SCHEMBL1243014 0.74 TSHR (0.32) TSHR
SCHEMBL1241854 0.73 TSHR (0.34) TSHR
SCHEMBL1241902 0.73 TSHR (0.34) TSHR
SCHEMBL1243038 0.73 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3732211-B1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-22 EP disclosed
US-11613600-B2 Capped dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-28 US disclosed
US-11492450-B2 Dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2022-11-08 US disclosed
US-11359035-B2 Multi- or dual-headed compositions useful for chain shuttling and process to prepare the same DOW GLOBAL TECHNOLOGIES LLC (US) 2022-06-14 US disclosed
US-20220073656-A1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC 2022-03-10 US disclosed
EP-3732211-A1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-11-04 EP disclosed
EP-3732181-A1 DUAL-HEADED ORGANOALUMINUM COMPOSITIONS Dow Global Technologies LLC (US) 2020-11-04 EP disclosed
US-20200339760-A1 DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2020-10-29 US disclosed
US-20200332045-A1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC 2020-10-22 US disclosed
EP-3489264-A1 CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies Llc (US) 2019-05-29 EP disclosed
EP-3243846-A2 MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies Llc (US) 2017-11-15 EP disclosed
EP-2459598-B1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-18 EP disclosed
US-8501885-B2 Dual- or multi-headed chain shuttling agents and their use for preparation of block copolymers DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-08-06 US disclosed
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 US disclosed
EP-0361477-B1 Method for manufacturing an alkenyl group-containing organopolysiloxane TORAY SILICONE CO (JP) 1994-07-27 EP disclosed
EP-0535687-A1 Preparation process of silicone resin WACKER-CHEMIE GMBH (DE) 1993-04-07 EP disclosed
US-4980439-A Method for manufacturing an alkenyl group-containing organopolysiloxane TORAY SILICONE COMPANY LIMITED (JP) 1990-12-25 US disclosed
EP-0361477-A2 Method for manufacturing an alkenyl group-containing organopolysiloxane TORAY SILICONE COMPANY, LIMITED (JP) 1990-04-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200332045-A1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS CAPG, C5, CDS2 TSHR 4645/4885
US-11613600-B2 Capped dual-headed organoaluminum compositions CAPG, C5, CDS2 TSHR 4645/4885
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS MSN, COASY, MCM7 TSHR 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.