SCHEMBL9344648

SCHEMBL9344648

CC[C@H]1CC[C@H](C2CCC(c3ccc(OC)cc3)CC2)CC1

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.53
SLC6A2 P23975 3/20 0.42
SLC6A4 P31645 3/20 0.42
SLC6A3 Q01959 3/20 0.42
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KDM1A O60341 2/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
GRM2 Q14416 1/20 0.39
THRB P10828 1/20 0.39
ESR1 P03372 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
ESR2 Q92731 1/20 0.39
DGAT1 O75907 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10762223 1.00 DRD2 (0.53) DRD2SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL25990680 1.00 DRD2 (0.53) DRD2SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL10762221 1.00 DRD2 (0.53) DRD2SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL10017476 0.95 DRD2 (0.57) DRD2SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL11282461 0.90 DRD2 (0.53) DRD2ALDH1A1MAPTSMN1; SMN2KDM1A
SCHEMBL8045452 0.87 DRD2 (0.54) DRD2ALDH1A1MAPTSMN1; SMN2KDM1A
SCHEMBL8045462 0.87 DRD2 (0.54) DRD2ALDH1A1MAPTSMN1; SMN2KDM1A
SCHEMBL7903735 0.87 DRD2 (0.54) DRD2ALDH1A1MAPTSMN1; SMN2KDM1A
SCHEMBL6463482 0.86 DRD2 (0.46) DRD2SLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL6463486 0.86 DRD2 (0.46) DRD2SLC6A2SLC6A4SLC6A3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0393636-B1 Liquid crystal composition and liquid crystal display using said composition CHISSO CORP (JP) 1994-07-20 EP disclosed
US-5258135-A Multiplexed displays, supertwisted birefringence effect CHISSO CORPORATION (JP) 1993-11-02 US disclosed
EP-0432780-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAID COMPOSITION CHISSO CORPORATION (JP) 1993-07-21 EP disclosed
US-5102577-A Supertwisted birefringence system CHISSO CORPORATION (JP) 1992-04-07 US disclosed
EP-0432780-A1 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1991-06-19 EP disclosed
EP-0393636-A2 Liquid crystal composition and liquid crystal display using said composition CHISSO CORPORATION (JP) 1990-10-24 EP disclosed
EP-0084974-B1 CARBOCYCLIC COMPOUNDS WITH LIQUID-CRYSTAL PROPERTIES Chisso Corporation (JP) 1986-04-02 EP disclosed
US-4477369-A New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same CHISSO CORPORATION (JP) 1984-10-16 US disclosed
EP-0084974-A1 Carbocyclic compounds with liquid-crystal properties Chisso Corporation (JP) 1983-08-03 EP disclosed