SCHEMBL934478

SCHEMBL934478

CC=C(C)C(=O)Oc1ccc(C(C)(C)c2ccc(O)cc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.50
ESR2 Q92731 4/20 0.50
CYP3A4 P08684 3/20 0.50
AR P10275 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A4 P31645 1/20 0.50
HTR6 P50406 1/20 0.50
ESRRG P62508 1/20 0.50
SLC6A3 Q01959 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH1A1 P00352 2/20 0.44
ELANE P08246 8/20 0.44
LMNA P02545 1/20 0.37
TYR P14679 1/20 0.37
MAPT P10636 2/20 0.36
BCHE P06276 1/20 0.36
CHRM2 P08172 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7457186 1.00 ESR1 (0.50) ESR1ESR2CYP3A4ARHPGD
SCHEMBL7457988 0.88 ELANE (0.44) ESR1ESR2ALDH1A1ELANELMNA
SCHEMBL215942 0.88 ELANE (0.44) ESR1ESR2ALDH1A1ELANELMNA
Triethylene Glycol SCHEMBL9233333 0.88 ESR1 (0.39) ESR1ESR2CYP3A4ARHPGD
SCHEMBL23422784 0.87 ESR1 (0.46) ESR1ESR2CYP3A4ARHPGD
SCHEMBL3863686 0.84 ESR1 (0.43) ESR1ESR2CYP3A4ARHPGD
SCHEMBL2169269 0.83 ESR2 (0.47) ESR1ESR2HSD17B10ELANELMNA
SCHEMBL6443549 0.83 MAPT (0.40) ESR1ESR2CYP3A4ARHPGD
SCHEMBL51951 0.83 ESR1 (0.52) ESR1ESR2CYP3A4ARHPGD
SCHEMBL130140 0.82 CYP3A4 (0.59) ESR1ESR2CYP3A4ARHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108299583-A A kind of cross-linking modified preparation method of special PVC resin 中国科学院新疆理化技术研究所 2018-07-20 CN claimed
CN-106659640-A Light-curing dental composite with increasing opacity 义获嘉伟瓦登特公司 2017-05-10 CN claimed
CN-104312460-B One pack system acrylic acid anaerobism bar glue and production method, construction method 广州双科新材料有限公司 2016-07-06 CN claimed
CN-105722494-A Impact modified denture base compositions 登士柏国际公司 2016-06-29 CN claimed
CN-105434179-A METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS CHARITE UNIV BE 2016-03-30 CN claimed
EP-2563869-B1 UV-CURABLE ACRYLATE BASED INK, A PROCESS AND AN INK BASE FOR ITS PRODUCTION PELIKAN HARDCOPY PRODUCTION AG (CH) 2015-08-05 EP claimed
CN-101495081-A Methods and tools for infiltrating enamel lesions CHARITE UNIVERSITAETSMEDIZIN (DE) 2009-07-29 CN claimed
CN-1112909-C Optimum particle sized hybrid composite KERR CORP (US) 2003-07-02 CN claimed
CN-1291090-A Composition for making temporary crowns and bridges KERR CORP (US) 2001-04-11 CN claimed
CN-1272781-A Hybrid composite material with optimum particle size KERR CORP (US) 2000-11-08 CN claimed
EP-0797785-B1 TEMPERATURE STABLE AND SUNLIGHT PROTECTED PHOTOCHROMIC ARTICLES CORNING INC (US) 2000-05-10 EP claimed
EP-0607414-B1 ANAEROBIC COMPOSITION WHICH EXPANDS WHEN POST CURED LOCTITE CORP (US) 1997-10-15 EP claimed
EP-0282633-B1 DENTAL PROSTHESIS MADE OF A SYNTHETIC MATERIAL Heraeus Kulzer GmbH (DE) 1991-05-08 EP claimed
CN-107075043-B Impact-resistant modified forming composition with improved performance profile 罗姆化学有限责任公司 2019-11-15 CN disclosed
CN-109891270-A For modulability contact lenses can casting, high refractive index, rigidity, gas-permeable polymer formulation object 威里利生命科学有限责任公司 2019-06-14 CN disclosed
CN-109627658-A Composition comprising the pure and mild Nano capsule containing liquid crystal media of functional polyethylene 默克专利股份有限公司 2019-04-16 CN disclosed
EP-0631598-B1 COMPOSITE DENTAL CEMENT COMPOSITION CONTAINING A LANTHANIDE SERIES COMPOUND ESSENTIAL DENTAL SYSTEMS INC (US) 1998-12-23 EP disclosed
EP-0593806-A1 Method for the preparation of a screen mesh for screen printing Schablonentechnik Kufstein Aktiengesellschaft (AT) 1994-04-27 EP disclosed
EP-0186789-B1 HYDROPHILIC COPOLYMERS, THEIR USE AS BIOMEDICAL MATERIALS AND CONTACT LENSES MADE OF THESE COPOLYMERS BAYER AG (DE) 1989-06-28 EP disclosed
EP-0186789-A2 Hydrophilic copolymers, their use as biomedical materials and contact lenses made of these copolymers BAYER AG (DE) 1986-07-09 EP disclosed