SCHEMBL130140

SCHEMBL130140

CC(=O)Oc1ccc(C(C)(C)c2ccc(O)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.59
ESR1 P03372 3/20 0.59
ESR2 Q92731 3/20 0.59
HSD17B10 Q99714 2/20 0.59
AR P10275 1/20 0.59
HPGD P15428 1/20 0.59
TSHR P16473 1/20 0.59
SLC6A2 P23975 1/20 0.59
SLC6A4 P31645 1/20 0.59
HTR6 P50406 1/20 0.59
ESRRG P62508 1/20 0.59
SLC6A3 Q01959 1/20 0.59
ELANE P08246 5/20 0.54
LMNA P02545 4/20 0.52
ALDH1A1 P00352 2/20 0.52
MAPT P10636 4/20 0.47
POLB P06746 1/20 0.47
PKM P14618 1/20 0.47
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5491320 0.92 LMNA (0.59) CYP3A4ESR1ESR2HSD17B10AR
SCHEMBL10629411 0.92 LMNA (0.59) CYP3A4ESR1ESR2HSD17B10AR
SCHEMBL253201 0.89 ESR1 (0.59) CYP3A4ESR1ESR2HSD17B10AR
SCHEMBL8862975 0.89 ESR1 (0.59) CYP3A4ESR1ESR2HSD17B10AR
Bicarbonate SCHEMBL2404791 0.87 ESR1 (0.57) CYP3A4ESR1ESR2HSD17B10AR
SCHEMBL11497534 0.87 ESR1 (0.61) CYP3A4ESR1ESR2HSD17B10AR
SCHEMBL22178622 0.87 LMNA (0.53) CYP3A4ESR1HSD17B10ARSLC6A2
SCHEMBL19829813 0.87 LMNA (0.53) CYP3A4ESR1HSD17B10ARSLC6A2
SCHEMBL808884 0.87 ESR1 (0.61) CYP3A4ESR1ESR2HSD17B10AR
SCHEMBL27411161 0.87 ESR1 (0.61) CYP3A4ESR1ESR2HSD17B10AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024132434-A1 POLYCARBONATE-SILOXANE COPOLYMER, COMPOSITION, AND METHOD OF MAKING THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2024-06-27 WO disclosed
US-20230151209-A1 LIQUID CRYSTAL POLYMER COMPOSITIONS AND CORRESPONDING ARTICLES SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-05-18 US disclosed
US-20220389217-A1 THERMOPLASTIC COMPOSITIONS AND SHAPED ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-08 US disclosed
US-20220389223-A1 THERMOPLASTIC COMPOSITIONS AND SHAPED ARTICLES THEREOF SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-12-08 US disclosed
EP-3798264-B1 REINFORCED FLAME RETARDANT POLYCARBONATE COMPOSITIONS WITH NANOSTRUCTURED FLUOROPOLYMER FOR THIN WALL APPLICATIONS SHPP GLOBAL TECH BV (NL) 2022-07-06 EP disclosed
US-11214583-B2 Compound having alkoxysilyl group and active ester group, method for preparing same, composition comprising same, and use KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2022-01-04 US disclosed
EP-3851495-A1 THERMOPLASTIC POLYCARBONATE COMPOSITIONS WITH IMPROVED HYDROLYTIC STABILITY AND ELECTRICAL TRACKING RESISTANCE AND SHAPED ARTICLES THEREOF SHPP Global Technologies B.V. (NL) 2021-07-21 EP disclosed
US-20210116761-A1 LIQUID CRYSTAL DISPLAY DEVICE SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) 2021-04-22 US disclosed
EP-3798265-A1 GLASS-FILLED FLAME RETARDANT POLYCARBONATE COMPOSITIONS AND THIN-WALLED ARTICLES THEREOF SHPP Global Technologies B.V. (NL) 2021-03-31 EP disclosed
US-20200165275-A1 COMPOUND HAVING ALKOXYSILYL GROUP AND ACTIVE ESTER GROUP, METHOD FOR PREPARING SAME, COMPOSITION COMPRISING SAME, AND USE KOREA INSTITUTE OF INDUSTRIAL TECHNOLOGY (KR) 2020-05-28 US disclosed
US-6924073-B2 Toner for developing electrostatic latent image, toner cartridge, developer, developer cartridge, image forming method, and image forming apparatus RICOH COMPANY, LTD. (JP) 2005-08-02 US disclosed
US-6911289-B2 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner RICOH COMPANY LIMITED (JP) 2005-06-28 US disclosed
US-6811944-B2 TONER HAVING A GOOD LOW TEMPERATURE FIXABILITY AND GOOD HIGH TEMPERATURE PRESERVABILITY, WITHOUT CAUSING A FILMING PROBLEM RICOH COMPANY LIMITED (JP) 2004-11-02 US disclosed
US-6813461-B2 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner RICOH COMPANY LIMITED (JP) 2004-11-02 US disclosed
US-20040166429-A1 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner HIGUCHI HIROTO (JP) 2004-08-26 US disclosed
US-20040166428-A1 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner HIGUCHI HIROTO (JP) 2004-08-26 US disclosed
US-6667141-B2 Charging surfaces; electrostatic latent images; development using toner RICOH COMPANY, LTD. (JP) 2003-12-23 US disclosed
US-20030165760-A1 Toner for developing electrostatic latent image, toner cartridge, developer, developer cartridge, image forming method, and image forming apparatus RICOH COMPANY, LTD. (JP) 2003-09-04 US disclosed
US-20020081513-A1 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner RICOH COMPANY LIMITED (JP) 2002-06-27 US disclosed
EP-1193563-A1 Toner, method for manufacturing the toner, and image forming method and apparatus using the toner Ricoh Company, Ltd. (JP) 2002-04-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200165275-A1 COMPOUND HAVING ALKOXYSILYL GROUP AND ACTIVE ESTER GROUP, METHOD FOR PREPARING SAME, COMPOSITION COMPRISING SAME, AND USE NOTUM, AGPS, ESD CYP3A4 234/4885ESR1 1248/4885ESR2 2607/4885
US-11214583-B2 Compound having alkoxysilyl group and active ester group, method for preparing same, composition comprising same, and use NOTUM, AGPS, ESD CYP3A4 234/4885ESR1 1248/4885ESR2 2607/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.