SCHEMBL9344846

SCHEMBL9344846

CO[Si](CCCNCCCCCCCCN)(OC)OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.50
CA2 P00918 3/20 0.50
CA4 P22748 3/20 0.50
CA6 P23280 3/20 0.50
CA5A P35218 3/20 0.50
CA7 P43166 3/20 0.50
CA9 Q16790 3/20 0.50
CA14 Q9ULX7 3/20 0.50
CA5B Q9Y2D0 3/20 0.50
F13A1 P00488 2/20 0.50
CYP1A2 P05177 2/20 0.50
ALOX15 P16050 2/20 0.50
THPO P40225 2/20 0.50
CA3 P07451 2/20 0.50
CA1 P00915 1/20 0.50
CYP2C9 P11712 1/20 0.50
PKM P14618 1/20 0.50
TSHR P16473 1/20 0.50
MTOR P42345 1/20 0.50
LMNA P02545 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49360 1.00 CA12 (0.50) CA12CA2CA4CA6CA5A
SCHEMBL2141806 1.00 CA12 (0.50) CA12CA2CA4CA6CA5A
SCHEMBL4443101 0.98 CA12 (0.52) CA12CA2CA4CA6CA5A
SCHEMBL5149878 0.96 CA12 (0.46) CA12CA2CA4CA6CA5A
SCHEMBL2059897 0.96 CA12 (0.46) CA12CA2CA4CA6CA5A
SCHEMBL31142020 0.94 CA12 (0.52) CA12CA2CA4CA6CA5A
SCHEMBL12190379 0.92 CA12 (0.50) CA12CA2CA4CA6CA5A
SCHEMBL2494932 0.92 CA12 (0.50) CA12CA2CA4CA6CA5A
SCHEMBL6120500 0.92 CA12 (0.44) CA12CA2CA4CA6CA5A
SCHEMBL8415425 0.91 CA12 (0.42) CA12CA2CA4CA6CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5002884-A Immobilization of physiologically active substances on an inorganic support TORAY SILICON COMPANY, LTD. (JP) 1991-03-26 US claimed
US-8029577-B2 Lightening and/or dyeing of human keratin fibres via a composition comprising a particular amino silicon compound and composition and device L'OREAL S.A. (FR) 2011-10-04 US disclosed
US-7909889-B2 Lightening and/or coloring human keratin fibers using at least one aminotrialkoxy silane or at least one aminotrialkenyloxy silane composition L'OREAL S.A. (FR) 2011-03-22 US disclosed
US-20100297049-A1 LIGHTENING AND/OR DYEING OF HUMAN KERATIN FIBRES BY MEANS OF A COMPOSITION COMPRISING A PARTICULAR AMINO SILICON COMPOUND AND COMPOSITION AND DEVICE L'OREAL S.A. (FR) 2010-11-25 US disclosed
US-20100275387-A1 LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION L'OREAL S.A. (FR) 2010-11-04 US disclosed
US-7695880-B2 Toner, electrophotographic apparatus and process cartridge CANON KABUSHIKI KAISHA (JP) 2010-04-13 US disclosed
US-20070281232-A1 TONER, ELECTROPHOTOGRAPHIC APPARATUS AND PROCESS CARTRIDGE CANON KABUSHIKI KAISHA (JP) 2007-12-06 US disclosed
EP-0325404-B1 Method of immobilizing physiologically active substances TORAY SILICONE CO (JP) 1994-08-10 EP disclosed
US-5002884-A Immobilization of physiologically active substances on an inorganic support TORAY SILICON COMPANY, LTD. (JP) 1991-03-26 US disclosed
EP-0325404-A2 Method of immobilizing physiologically active substances Toray Silicone Company, Ltd. (JP) 1989-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100275387-A1 LIGHTENING AND/OR COLORING HUMAN KERATIN FIBERS USING AT LEAST ONE AMINOTRIALKOXY SILANE OR AT LEAST ONE AMINOTRIALKENYLOXY SILANE COMPOSITION KRT18, FABP4, ALDH7A1 CA12 723/4885CA2 1667/4885CA4 1676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.