SCHEMBL9345185

SCHEMBL9345185

CCCCC1CCC(c2ccc(OCCCC3CCC(CCC)CC3)cc2)CC1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 5/20 0.50
RAB9A P51151 1/20 0.50
LMNA P02545 2/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
MEN1 O00255 1/20 0.48
MAPK1 P28482 1/20 0.48
KMT2A Q03164 1/20 0.48
HRH3 Q9Y5N1 6/20 0.46
CRBN Q96SW2 1/20 0.44
KCNH2 Q12809 3/20 0.43
NPC1 O15118 1/20 0.43
CYP3A4 P08684 3/20 0.42
S1PR3 Q99500 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9346164 1.00 CYP2C9 (0.50) CYP2C9RAB9ALMNAALDH1A1MAPT
SCHEMBL9346177 1.00 CYP2C9 (0.50) CYP2C9RAB9ALMNAALDH1A1MAPT
SCHEMBL9345177 1.00 CYP2C9 (0.50) CYP2C9RAB9ALMNAALDH1A1MAPT
SCHEMBL9346076 0.97 CYP2C9 (0.52) CYP2C9RAB9ALMNAALDH1A1MAPT
SCHEMBL9346062 0.97 CYP2C9 (0.52) CYP2C9RAB9ALMNAALDH1A1MAPT
SCHEMBL9344389 0.97 RAB9A (0.52) CYP2C9RAB9ALMNAALDH1A1MAPT
SCHEMBL9344379 0.97 RAB9A (0.52) CYP2C9RAB9ALMNAALDH1A1MAPT
SCHEMBL9349293 0.96 RAB9A (0.49) CYP2C9RAB9ALMNAALDH1A1MAPT
SCHEMBL9349312 0.96 RAB9A (0.49) CYP2C9RAB9ALMNAALDH1A1MAPT
SCHEMBL9344279 0.96 RAB9A (0.49) CYP2C9RAB9ALMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0344557-B1 Liquid crystal components with a trimethylenoxy group HOFFMANN LA ROCHE (CH) 1994-08-10 EP disclosed
US-5238600-A IBIMETHYLENOXY CONTAINING LIQUID CRYSTAL COMPOUNDS HOFFMANN-LA ROCHE INC. (US) 1993-08-24 US disclosed
EP-0344557-A2 Liquid crystal components with a trimethylenoxy group F. HOFFMANN-LA ROCHE AG (CH) 1989-12-06 EP disclosed