Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.56 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 6/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | AKT1 | P31749 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27328511 | 0.85 | TRPV1 (0.52) | CYP4F2CYP4A11TRPV1CCR5LTA4H | |
| SCHEMBL2417527 | 0.85 | PTGS1 (0.48) | CYP4F2CYP4A11TRPV1CCR5ALOX15 | |
| SCHEMBL3351439 | 0.84 | CASR (0.50) | CYP4F2CYP4A11TRPV1CCR5LTA4H | |
| SCHEMBL178977 | 0.82 | TRPV1 (0.57) | CYP4F2CYP4A11TRPV1CCR5LTA4H | |
| SCHEMBL491276 | 0.82 | CYP4F2 (0.59) | CYP4F2CYP4A11LTA4HDRD2 | |
| SCHEMBL2848440 | 0.82 | CYP4F2 (0.59) | CYP4F2CYP4A11CYP4Z1 | |
| SCHEMBL10338797 | 0.81 | CCR5 (0.57) | CYP4F2CYP4A11TRPV1CCR5LTA4H | |
| SCHEMBL9588895 | 0.81 | TRPV1 (0.60) | CYP4F2CYP4A11TRPV1CCR5LTA4H | |
| SCHEMBL10439122 | 0.80 | TRPV1 (0.53) | CYP4F2CYP4A11TRPV1CCR5LTA4H | |
| SCHEMBL178978 | 0.79 | TRPV1 (0.58) | CYP4F2CYP4A11TRPV1CCR5LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333522-B1 | Catechol derivatives and pharmaceutical preparations containing same | MITSUI TOATSU CHEMICALS (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5232923-A | Stimulates production of nerve growth factor; administering for treatment of regressive disorders of the central nervous system | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0333522-A2 | Catechol derivatives and pharmaceutical preparations containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-20 | — | — | EP | disclosed |