Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.38 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349057 | 1.00 | RAB9A (0.51) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9349391 | 1.00 | RAB9A (0.51) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9346339 | 1.00 | RAB9A (0.51) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9344398 | 1.00 | RAB9A (0.51) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9344238 | 0.99 | RAB9A (0.52) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9345444 | 0.98 | RAB9A (0.53) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9345766 | 0.96 | RAB9A (0.51) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9593565 | 0.93 | RAB9A (0.48) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9345157 | 0.91 | RAB9A (0.45) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL9589366 | 0.91 | RAB9A (0.53) | RAB9ALMNAMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344557-B1 | Liquid crystal components with a trimethylenoxy group | HOFFMANN LA ROCHE (CH) | 1994-08-10 | — | — | EP | disclosed |
| US-5238600-A | IBIMETHYLENOXY CONTAINING LIQUID CRYSTAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 1993-08-24 | — | — | US | disclosed |