Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.80 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | GMNN | O75496 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | IDE | P14735 | 1/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrocaffeoylhexylamide SCHEMBL9346647 | 1.00 | TRPV1 (0.80) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL9350021 | 1.00 | TRPV1 (0.80) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL9345431 | 0.99 | TRPV1 (0.78) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL9425343 | 0.94 | TRPV1 (0.75) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL8390662 | 0.90 | TRPV1 (0.87) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| Palmitoyl Dopamine SCHEMBL875454 | 0.89 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL30582326 | 0.89 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL10617939 | 0.89 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL3326638 | 0.89 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL30368905 | 0.89 | TRPV1 (1.00) | TRPV1MAPTHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333522-B1 | Catechol derivatives and pharmaceutical preparations containing same | MITSUI TOATSU CHEMICALS (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5232923-A | Stimulates production of nerve growth factor; administering for treatment of regressive disorders of the central nervous system | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0333522-A2 | Catechol derivatives and pharmaceutical preparations containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-20 | — | — | EP | disclosed |