Palmitoyl Dopamine

Palmitoyl Dopamine

SCHEMBL875454

CCCCCCCCCCCCCCCC(=O)NCCc1ccc(O)c(O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 5/20 1.00
MAPT P10636 4/20 1.00
HSD17B10 Q99714 2/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
HPGD P15428 2/20 0.86
KDM4E B2RXH2 1/20 0.86
NPC1 O15118 1/20 0.86
GMNN O75496 1/20 0.86
USP2 O75604 1/20 0.86
LMNA P02545 1/20 0.86
TP53 P04637 1/20 0.86
CYP1A2 P05177 1/20 0.86
POLB P06746 1/20 0.86
CYP3A4 P08684 1/20 0.86
CYP2C9 P11712 1/20 0.86
IDE P14735 1/20 0.86
ALOX15 P16050 1/20 0.86
NFKB1 P19838 1/20 0.86
MAPK1 P28482 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3617723 1.00 TRPV1 (1.00) TRPV1MAPTHSD17B10MEN1KMT2A
SCHEMBL30368905 1.00 TRPV1 (1.00) TRPV1MAPTHSD17B10MEN1KMT2A
SCHEMBL30718914 1.00 TRPV1 (1.00) TRPV1MAPTHSD17B10MEN1KMT2A
SCHEMBL30718949 1.00 TRPV1 (1.00) TRPV1MAPTHSD17B10MEN1KMT2A
Palmitoyl Dopamine SCHEMBL30438287 1.00 TRPV1 (1.00) TRPV1MAPTHSD17B10MEN1KMT2A
SCHEMBL30582326 1.00 TRPV1 (1.00) TRPV1MAPTHSD17B10MEN1KMT2A
SCHEMBL10617939 1.00 TRPV1 (1.00) TRPV1MAPTHSD17B10MEN1KMT2A
SCHEMBL3326638 1.00 TRPV1 (1.00) TRPV1MAPTHSD17B10MEN1KMT2A
SCHEMBL3325854 1.00 TRPV1 (1.00) TRPV1MAPTHSD17B10MEN1KMT2A
SCHEMBL671000 1.00 TRPV1 (1.00) TRPV1MAPTHSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118879891-A Method for evaluating PE (polyethylene) based on intestinal flora 广州市番禺区妇幼保健院(广州市番禺区何贤纪念医院) 2024-11-01 CN claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
EP-3207091-B1 IMPROVED RUBBER COMPOSITIONS AND USES THEREOF BRIDGESTONE CORP (JP) 2019-09-18 EP claimed
CN-118879891-A Method for evaluating PE (polyethylene) based on intestinal flora 广州市番禺区妇幼保健院(广州市番禺区何贤纪念医院) 2024-11-01 CN disclosed
WO-2024124172-A1 COMPOSITIONS AND METHODS FOR STIMULATING AND/OR ENHANCING EXERCISE MOTIVATION AND/OR PHYSICAL PERFORMANCE THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2024-06-13 WO disclosed
US-20200323814-A1 MEDICAL COMPOUND VERA SALUS RICERCA S.R.L. (IT) 2020-10-15 US disclosed
WO-2019008537-A9 MEDICAL COMPOUNDS VERA SALUS RICERCA S.R.L. (IT) 2020-02-20 WO disclosed
WO-2019008537-A1 MEDICAL COMPOUNDS VERA SALUS RICERCA S.R.L. (IT) 2019-01-10 WO disclosed
EP-2618802-A1 COSMETIC TREATMENT PROCESS USING ORTHO-DIPHENOL DERIVATIVES, NOVEL COMPOUNDS AND COSMETIC COMPOSITION COMPRISING SAME L'Oréal (FR) 2013-07-31 EP disclosed
WO-2012038334-A1 COSMETIC TREATMENT PROCESS USING ORTHO-DIPHENOL DERIVATIVES, NOVEL COMPOUNDS AND COSMETIC COMPOSITION COMPRISING SAME L'OREAL (FR) 2012-03-29 WO disclosed
WO-2012038334-A1 COSMETIC TREATMENT PROCESS USING ORTHO-DIPHENOL DERIVATIVES, NOVEL COMPOUNDS AND COSMETIC COMPOSITION COMPRISING SAME L'OREAL (FR) 2012-03-29 WO disclosed
US-20100130603-A1 MEDICAMENT FOR PROPHYLACTIC AND THERAPEUTIC TREATMENT OF DERMATOSIS RESULTING FROM EXCESSIVELY ADVANCED KERATINIZATION KYOTO UNIVERSITY (JP) 2010-05-27 US disclosed
EP-2127673-A1 PHARMACEUTICAL AGENT FOR PREVENTION AND TREATMENT OF SKIN DISEASE INDUCED BY ACCELERATED KERATINIZATION Kyoto University (JP) 2009-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200323814-A1 MEDICAL COMPOUND MTNR1B, CBR1, MTNR1A TRPV1 2045/4885MAPT 3940/4885HSD17B10 732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.