SCHEMBL9345685

SCHEMBL9345685

CCC(=O)C1=C(O)CC(c2cccc(O)c2)CC1=O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.53
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
MAPT P10636 3/20 0.48
KDM4E B2RXH2 1/20 0.48
GAA P10253 1/20 0.48
DRD2 P14416 3/20 0.42
DRD3 P35462 2/20 0.41
HTT P42858 3/20 0.41
ALDH1A1 P00352 3/20 0.41
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9343912 0.87 RAB9A (0.48) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL10921989 0.85 RAB9A (0.49) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL9348719 0.83 RAB9A (0.54) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL10740619 0.82 RAB9A (0.51) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL9182655 0.81 HTT (0.53) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL9343924 0.80 RAB9A (0.51) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL9343905 0.80 RAB9A (0.44) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL9722685 0.79 RAB9A (0.44) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL9722645 0.79 RAB9A (0.44) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL9343901 0.78 RAB9A (0.52) RAB9AMEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450711-B1 Substituted cyclohexanediones and their herbicidal uses DOWELANCO (US) 1994-07-13 EP disclosed
WO-1991015119-A1 SUBSTITUTED CYCLOHEXANEDIONES AND THEIR HERBICIDAL USES DOWELANCO (US) 1991-10-17 WO disclosed
WO-1991015123-A1 SUBSTITUTED CYCLOHEXANEDIONES AND THEIR HERBICIDAL USES DOWELANCO (US) 1991-10-17 WO disclosed
EP-0450711-A1 Substituted cyclohexanediones and their herbicidal uses DOWELANCO (US) 1991-10-09 EP disclosed
EP-0449385-A2 Substituted cyclohexanediones and their herbicidal uses DOWELANCO (US) 1991-10-02 EP disclosed
US-5006159-A Oximes, effective against grassy weeds but selective to broadleaf crops such as cotton, sugar beets, soybeans, wheat, rice and corn DOWELANCO (US) 1991-04-09 US disclosed
US-4983211-A Substituted cyclohexanediones and their herbicidal use DOWELANCO (US) 1991-01-08 US disclosed