Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | PNP | P00491 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9345725 | 1.00 | HIF1A (0.58) | HIF1APOLBENPP1P2RY1PNP | |
| Hydrochloric Acid SCHEMBL2005857 | 0.99 | HIF1A (0.57) | HIF1APOLBENPP1P2RY1PNP | |
| Hydrochloric Acid SCHEMBL2005855 | 0.99 | HIF1A (0.57) | HIF1APOLBENPP1P2RY1PNP | |
| Deoxyinosine SCHEMBL2000526 | 0.89 | HIF1A (0.73) | HIF1APNPLMNATP53HTT | |
| Deoxyinosine SCHEMBL5982293 | 0.89 | HIF1A (0.73) | HIF1APNPLMNATP53HTT | |
| Deoxyinosine SCHEMBL324457 | 0.89 | HIF1A (0.73) | HIF1APNPLMNATP53HTT | |
| Deoxyinosine SCHEMBL7191121 | 0.89 | HIF1A (0.73) | HIF1APNPLMNATP53HTT | |
| Deoxyinosine SCHEMBL24307 | 0.89 | HIF1A (0.73) | HIF1APNPLMNATP53HTT | |
| SCHEMBL6914336 | 0.88 | POLB (0.63) | HIF1APOLBENPP1P2RY1PNP | |
| SCHEMBL6914328 | 0.88 | POLB (0.63) | HIF1APOLBENPP1P2RY1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270651-B1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INST OF TECHN (US) | 1994-06-15 | — | — | EP | disclosed |
| US-5217866-A | Polynucleotide assay reagent and method | ANTI-GENE DEVELOPMENT GROUP (US) | 1993-06-08 | — | — | US | disclosed |
| US-5118800-A | Oligonucleotides possessing a primary amino group in the terminal nucleotide | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5118802-A | DNA-reporter conjugates linked via the 2' or 5'-primary amino group of the 5'-terminal nucleoside | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1992-06-02 | — | — | US | disclosed |
| US-5015733-A | Phosphoramidites and oligonucleotides derived therefrom | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1991-05-14 | — | — | US | disclosed |
| US-4849513-A | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0270651-A4 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1989-03-29 | — | — | EP | disclosed |
| EP-0270651-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES. | CALIFORNIA INST OF TECHN (US) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988000201-A1 | NOVEL DEOXYRIBONUCLEOSIDE PHOSPHORAMIDITES AND THEIR USE FOR THE PREPARATION OF OLIGONUCLEOTIDES | CALIFORNIA INSTITUTE OF TECHNOLOGY, INC. (US) | 1988-01-14 | — | — | WO | disclosed |