Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9344573 | 1.00 | LMNA (0.39) | LMNANR5A1CRBNNPC1S1PR3 | |
| SCHEMBL9345716 | 1.00 | LMNA (0.39) | LMNANR5A1CRBNNPC1S1PR3 | |
| SCHEMBL9346067 | 1.00 | LMNA (0.39) | LMNANR5A1CRBNNPC1S1PR3 | |
| SCHEMBL9346429 | 0.99 | LMNA (0.40) | LMNANR5A1CRBNNPC1S1PR3 | |
| SCHEMBL9348876 | 0.99 | LMNA (0.40) | LMNANR5A1CRBNNPC1S1PR3 | |
| SCHEMBL9344362 | 0.97 | LMNA (0.40) | LMNANR5A1CRBNNPC1S1PR3 | |
| SCHEMBL9345991 | 0.97 | LMNA (0.40) | LMNANR5A1CRBNNPC1S1PR3 | |
| SCHEMBL9344528 | 0.97 | LMNA (0.40) | LMNANR5A1CRBNNPC1S1PR3 | |
| SCHEMBL9344348 | 0.97 | LMNA (0.40) | LMNANR5A1CRBNNPC1S1PR3 | |
| SCHEMBL9346001 | 0.97 | LMNA (0.40) | LMNANR5A1CRBNNPC1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344557-B1 | Liquid crystal components with a trimethylenoxy group | HOFFMANN LA ROCHE (CH) | 1994-08-10 | — | — | EP | disclosed |
| EP-0344557-A2 | Liquid crystal components with a trimethylenoxy group | F. HOFFMANN-LA ROCHE AG (CH) | 1989-12-06 | — | — | EP | disclosed |