Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839814 | 0.94 | EPHX2 (0.64) | HPGDALDH1A1EPHX2TRPV1FAAH | |
| SCHEMBL9840800 | 0.94 | EPHX2 (0.64) | HPGDALDH1A1EPHX2TRPV1FAAH | |
| SCHEMBL934546 | 0.83 | TDP1 (0.49) | HPGDHDAC8HDAC6KDM4EPOLB | |
| SCHEMBL9480522 | 0.78 | THRB (0.49) | HPGDHDAC1HDAC8HDAC6POLB | |
| SCHEMBL26749658 | 0.77 | HPGD (0.76) | HPGDALDH1A1EPHX2HDAC3HDAC4 | |
| SCHEMBL4401015 | 0.77 | EPHX2 (0.87) | HPGDALDH1A1EPHX2HDAC3HDAC4 | |
| SCHEMBL2852749 | 0.77 | HPGD (0.43) | HPGDHDAC8HDAC6POLB | |
| SCHEMBL9430237 | 0.76 | GRM5 (0.50) | HPGDALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL18415486 | 0.76 | GRM5 (0.53) | HPGDALDH1A1HDAC1HDAC8HDAC6 | |
| SCHEMBL11702609 | 0.76 | HPGD (0.73) | HPGDALDH1A1EPHX2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006935-A2 | TETRAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2011-01-20 | — | — | WO | disclosed |