Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.82 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | PYGL | P06737 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9444656 | 0.95 | TRPV1 (0.78) | TRPV1HPGDLTA4HMEN1KMT2A | |
| SCHEMBL14763513 | 0.90 | TRPV1 (1.00) | TRPV1HPGDHSD17B10MEN1MAPT | |
| SCHEMBL10946174 | 0.88 | TRPV1 (0.70) | TRPV1HPGD | |
| SCHEMBL179093 | 0.87 | TRPV1 (0.77) | TRPV1MEN1MAPTKMT2A | |
| SCHEMBL179009 | 0.83 | TRPV1 (0.79) | TRPV1MEN1MAPTKMT2A | |
| SCHEMBL29548277 | 0.82 | TRPV1 (0.78) | TRPV1HPGDMEN1MAPTKMT2A | |
| SCHEMBL179091 | 0.82 | TRPV1 (0.62) | TRPV1MEN1KMT2A | |
| SCHEMBL11367962 | 0.81 | HPGD (0.82) | TRPV1HPGDPYGLHSD17B10MEN1 | |
| SCHEMBL108284 | 0.81 | TRPV1 (0.67) | TRPV1MEN1MAPTKMT2A | |
| SCHEMBL9589809 | 0.80 | TRPV1 (0.65) | TRPV1HPGDLTA4HHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0333522-B1 | Catechol derivatives and pharmaceutical preparations containing same | MITSUI TOATSU CHEMICALS (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5232923-A | Stimulates production of nerve growth factor; administering for treatment of regressive disorders of the central nervous system | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-08-03 | — | — | US | disclosed |
| EP-0333522-A2 | Catechol derivatives and pharmaceutical preparations containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1989-09-20 | — | — | EP | disclosed |