Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.65 |
| ▸ | LTA4H | P09960 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | AKT1 | P31749 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 3/20 | 0.48 |
| ▸ | CFD | P00746 | 1/20 | 0.47 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.47 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178978 | 0.91 | TRPV1 (0.58) | TRPV1LTA4HALOX15PTGS1AKT1 | |
| SCHEMBL9588895 | 0.90 | TRPV1 (0.60) | TRPV1LTA4HALOX15PTGS1AKT1 | |
| SCHEMBL178977 | 0.88 | TRPV1 (0.57) | TRPV1LTA4HALOX15PTGS1AKT1 | |
| SCHEMBL15549411 | 0.85 | ALOX15 (0.65) | TRPV1LTA4HALOX15PPARGPPARA | |
| SCHEMBL15548241 | 0.84 | ALOX15 (0.68) | TRPV1LTA4HALOX15PPARGPPARA | |
| SCHEMBL17253827 | 0.83 | CYP4F2 (0.54) | TRPV1LTA4HALOX15PTGS1AKT1 | |
| SCHEMBL108828 | 0.83 | TRPV1 (0.51) | TRPV1LTA4HPTGS1AKT1ALDH1A1 | |
| SCHEMBL9751110 | 0.83 | TRPV1 (0.48) | TRPV1LTA4HALOX15PPARGPPARA | |
| SCHEMBL107425 | 0.83 | TRPV1 (0.51) | TRPV1LTA4HPTGS1AKT1ALDH1A1 | |
| SCHEMBL15559089 | 0.83 | ALOX15 (0.74) | TRPV1LTA4HALOX15PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214034-A | Improved secretion of nerve growth factor | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-05-25 | — | — | US | disclosed |
| US-5102906-A | Alzheimer*s disease | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0261977-B1 | CATECHOL DERIVATIVES, AND PREVENTIVE AND REMEDIAL PREPARATIONS FOR REGRESSIVE DISORDERS IN THE CENTRAL NERVOUS SYSTEM | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4985458-A | TREATMENT OF ALZHEIMER*S DISEASE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0261977-A2 | Catechol derivatives, and preventive and remedial preparations for regressive disorders in the central nervous system | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1988-03-30 | — | — | EP | disclosed |