Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 2/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347255 | 0.88 | SMN1; SMN2 (0.34) | CYP3A4HTTSMN1; SMN2SMYD2AGXT | |
| SCHEMBL1314001 | 0.84 | AGXT (0.42) | CYP3A4HTTSMN1; SMN2SMYD2AGXT | |
| SCHEMBL9347236 | 0.83 | AGXT (0.33) | CYP3A4HTTSMN1; SMN2SMYD2AGXT | |
| SCHEMBL11934179 | 0.81 | TP53 (0.42) | CYP3A4HTTSMN1; SMN2SMYD2AGXT | |
| SCHEMBL9347235 | 0.81 | ESR1 (0.43) | CYP3A4IDO1PPARG | |
| SCHEMBL14542685 | 0.81 | AGXT (0.43) | CYP3A4HTTSMN1; SMN2AGXTIDO1 | |
| SCHEMBL2745018 | 0.80 | PPARG (0.41) | PPARG | |
| SCHEMBL4587307 | 0.80 | IDO1 (0.42) | HTTSMN1; SMN2IDO1 | |
| SCHEMBL222047 | 0.80 | MAOB (0.43) | SMN1; SMN2AGXTIDO1 | |
| SCHEMBL14546351 | 0.79 | SIGMAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236880-B1 | Penem derivatives | ERBA CARLO SPA (IT) | 1994-07-20 | — | — | EP | disclosed |
| US-4886793-A | PENICILLINS; HUMANS OR ANIMALS | FARMITALIA CARLO ERBA, S.R.L. (IT) | 1989-12-12 | — | — | US | disclosed |
| EP-0236880-A2 | Penem derivatives | FARMITALIA CARLO ERBA S.r.l. (IT) | 1987-09-16 | — | — | EP | disclosed |