SCHEMBL9347287

SCHEMBL9347287

NC(CCC(=O)N[C@@H](CS)C(=O)O)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 2/20 0.70
GSTK1 Q9Y2Q3 1/20 0.70
NOD1 Q9Y239 9/20 0.57
FOLH1 Q04609 3/20 0.50
ALOX15 P16050 2/20 0.48
BLM P54132 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
THRB P10828 1/20 0.48
NFKB1 P19838 1/20 0.48
PTGS2 P35354 1/20 0.48
THPO P40225 1/20 0.48
RECQL P46063 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
GRM8 O00222 1/20 0.48
GRM6 O15303 1/20 0.48
GRIN2D O15399 1/20 0.48
GRIN3B O60391 1/20 0.48
GSR P00390 1/20 0.48
CYP1A2 P05177 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121501 1.00 PTGS1 (0.70) PTGS1GSTK1NOD1FOLH1ALOX15
SCHEMBL15420876 1.00 PTGS1 (0.70) PTGS1GSTK1NOD1FOLH1ALOX15
SCHEMBL121500 1.00 PTGS1 (0.70) PTGS1GSTK1NOD1FOLH1ALOX15
SCHEMBL2509561 1.00 PTGS1 (0.70) PTGS1GSTK1NOD1FOLH1ALOX15
SCHEMBL15420877 1.00 PTGS1 (0.70) PTGS1GSTK1NOD1FOLH1ALOX15
SCHEMBL27709907 1.00 PTGS1 (0.70) PTGS1GSTK1NOD1FOLH1ALOX15
Water SCHEMBL9548430 0.98 PTGS1 (0.68) PTGS1GSTK1NOD1FOLH1ALOX15
SCHEMBL29265136 0.98 PTGS1 (0.68) PTGS1GSTK1NOD1FOLH1ALOX15
SCHEMBL28993717 0.98 PTGS1 (0.68) PTGS1GSTK1NOD1FOLH1ALOX15
Cysteine SCHEMBL5355161 0.97 PTGS1 (0.67) PTGS1GSTK1NOD1FOLH1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59192088-A None JP disclosed
JP-1228473-A None JP disclosed
US-20230136465-A1 PLANT-BASED CHICKEN FLAVORING AGENT COMPOSITION NotCo Delaware AI, LLC 2023-05-04 US disclosed
EP-4161498-A1 TREATMENT OF CYSTINOSIS NaCuity Pharmaceuticals, Inc. (US) 2023-04-12 EP disclosed
EP-4093389-A1 PRODRUG FOR THE TREATMENT OF DISEASE AND INJURY OF OXIDATIVE STRESS NaCuity Pharmaceuticals, Inc. (US) 2022-11-30 EP disclosed
US-11504413-B2 Multi-nutrient composition EXERKINE CORPORATION (CA) 2022-11-22 US disclosed
WO-2022204221-A1 TREATMENT OF FERROPTOSIS NACUITY PHARMACEUTICALS, INC. (US) 2022-09-29 WO disclosed
EP-4000612-A1 TREATMENT OF RETINITIS PIGMENTOSA WITH N-ACETYLCYSTEINE AMIDE The Johns Hopkins University (US) 2022-05-25 EP disclosed
US-20220062368-A1 Weight Management Composition MCMASTER UNIVERSITY (CA) 2022-03-03 US disclosed
US-11167001-B2 Weight management composition EXERKINE CORPORATION (CA) 2021-11-09 US disclosed
US-20090042822-A1 METHOD TO ENHANCE DELIVERY OF GLUTATHIONE AND ATP LEVELS IN CELLS BIOCEUTICALS, INC. (US) 2009-02-12 US disclosed
EP-0387067-B1 Novel recombinant DNA and method for production of physiologically active substance KIKKOMAN CORP (JP) 1994-08-31 EP disclosed
EP-0387067-A1 Novel recombinant DNA and method for production of physiologically active substance KIKKOMAN CORPORATION (JP) 1990-09-12 EP disclosed
JP-H01228473-A PRODUCTION ON NOVEL RECOMBINANT DNA AND GLUTATHIONE KIMURA HIKARI 1989-09-12 JP disclosed
US-4596775-A Escherichia coli which produces gamma-glutamyl-L-cysteine synthetase AKIRA KIMURA (JP) 1986-06-24 US disclosed
US-4596775-A Escherichia coli which produces gamma-glutamyl-L-cysteine synthetase AKIRA KIMURA (JP) 1986-06-24 US disclosed
JP-S59192088-A PLASMID FORMED BY GENE RECOMBINATION AND PREPARATION OF GLUTHATHIONE BY IT KIMURA HIKARI 1984-10-31 JP disclosed
EP-0071485-A2 Novel microorganisms derived from microorganisms of the genus Escherichia by mutation and their use in the preparation of glutathione Kimura, Akira (JP) 1983-02-09 EP disclosed
EP-0071485-A2 Novel microorganisms derived from microorganisms of the genus Escherichia by mutation and their use in the preparation of glutathione Kimura, Akira (JP) 1983-02-09 EP disclosed
EP-0071486-A2 Novel microorganisms of the genus Eschericia, hybrid DNA for use in their production and the use of the microorganisms in the preparation of glutathione Kimura, Akira (JP) 1983-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090042822-A1 METHOD TO ENHANCE DELIVERY OF GLUTATHIONE AND ATP LEVELS IN CELLS GSR, TXNRD2, TXNRD1 PTGS1 435/4885GSTK1 36/4885NOD1 3311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.