Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347275 | 0.81 | KDM4E (0.35) | KDM4EATMRECQL | |
| SCHEMBL9402893 | 0.77 | APEX1 (0.34) | KDM4EAPEX1CA1CA2CA9 | |
| SCHEMBL7613158 | 0.76 | CA1 (0.37) | KDM4EATMAPEX1CA1CA2 | |
| SCHEMBL7607426 | 0.76 | CA1 (0.37) | KDM4EATMAPEX1CA1CA2 | |
| SCHEMBL9347011 | 0.76 | CA1 (0.41) | KDM4EATMAPEX1CA1CA2 | |
| SCHEMBL9402839 | 0.74 | MAPK14 (0.37) | KDM4EAPEX1RECQL | |
| SCHEMBL9347245 | 0.74 | KDM4E (0.33) | KDM4ERECQL | |
| SCHEMBL14640748 | 0.73 | KDM4E (0.44) | KDM4EATMAPEX1CA1CA2 | |
| SCHEMBL9347256 | 0.73 | MAPK14 (0.40) | KDM4EAPEX1RECQL | |
| SCHEMBL26607 | 0.72 | CA1 (0.41) | KDM4EATMAPEX1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298644-A | Aryl phosphinites | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-29 | — | — | US | disclosed |