SCHEMBL9402893

SCHEMBL9402893

Cc1cc(C)c(P(Oc2ccc(C(C)(C)C)cc2C(C)(C)C)c2ccccc2)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.34
KDM4E B2RXH2 2/20 0.33
MRGPRX4 Q96LA9 1/20 0.33
LMNA P02545 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6819958 0.86 APEX1 (0.40) APEX1KDM4EMRGPRX4CA1CA2
SCHEMBL7615315 0.84 APEX1 (0.39) APEX1KDM4EMRGPRX4CA1CA2
SCHEMBL9402839 0.81 MAPK14 (0.37) APEX1KDM4ELMNA
SCHEMBL13199358 0.80 APEX1 (0.32) APEX1KDM4EMRGPRX4
SCHEMBL7115234 0.79 APEX1 (0.39) APEX1KDM4EMRGPRX4CA1CA2
SCHEMBL31556870 0.79 APEX1 (0.39) APEX1KDM4EMRGPRX4CA1CA2
SCHEMBL9402856 0.78 RXRA (0.37) APEX1CA1CA2CA9
SCHEMBL9347300 0.77 KDM4E (0.34) APEX1KDM4ECA1CA2CA9
SCHEMBL2960192 0.76 APEX1 (0.40) APEX1KDM4EMRGPRX4CA1CA2
SCHEMBL9347011 0.75 CA1 (0.41) APEX1KDM4ELMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5281640-A For thermoplastic or thermosetting plastics, polymer-containing polymerized mono- or diolefin molding materials HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-25 US disclosed