Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.49 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.49 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347337 | 1.00 | DGAT1 (0.55) | DGAT1FAAHCHRM2SOAT1DGAT2 | |
| SCHEMBL9347105 | 0.85 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL9347109 | 0.85 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL2259544 | 0.84 | ESR2 (0.62) | DGAT1FAAHCHRM2SOAT1DGAT2 | |
| SCHEMBL462294 | 0.84 | ESR2 (0.62) | DGAT1FAAHCHRM2SOAT1DGAT2 | |
| SCHEMBL18763873 | 0.84 | ESR2 (0.62) | DGAT1FAAHCHRM2SOAT1DGAT2 | |
| SCHEMBL17318281 | 0.84 | IDO1 (0.57) | DGAT1FAAHCHRM2SOAT1DGAT2 | |
| SCHEMBL3538810 | 0.84 | IDO1 (0.57) | DGAT1FAAHCHRM2SOAT1DGAT2 | |
| SCHEMBL3538808 | 0.84 | IDO1 (0.57) | DGAT1FAAHCHRM2SOAT1DGAT2 | |
| SCHEMBL3537767 | 0.83 | DGAT1 (0.56) | DGAT1FAAHCHRM2SOAT1DGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272580-B1 | Liquidcrystalline cyclohexylbenzene derivatives their manufacturing and novel nematic admixtures containing same | WOJSKOWA AKAD TECH (PL) | 1994-08-17 | — | — | EP | disclosed |
| EP-0272580-A2 | Liquidcrystalline cyclohexylbenzene derivatives their manufacturing and novel nematic admixtures containing same | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1988-06-29 | — | — | EP | disclosed |