Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300908 | 0.85 | NPC1 (0.58) | NAMPTSLC18A3TRPV6PGRLMNA | |
| SCHEMBL3300911 | 0.85 | NPC1 (0.58) | NAMPTSLC18A3TRPV6PGRLMNA | |
| SCHEMBL1066991 | 0.84 | SLC18A3 (0.57) | NAMPTSLC18A3ALDH1A1TRPV6GAA | |
| SCHEMBL15911925 | 0.84 | SLC18A3 (0.57) | NAMPTSLC18A3ALDH1A1TRPV6GAA | |
| Hydrochloric Acid SCHEMBL9347470 | 0.84 | NPC1 (0.57) | NAMPTSLC18A3TRPV6PGRLMNA | |
| Hydrochloric Acid SCHEMBL9347478 | 0.84 | NPC1 (0.57) | NAMPTSLC18A3TRPV6PGRLMNA | |
| SCHEMBL9351302 | 0.80 | SLC18A3 (0.46) | NAMPTSLC18A3ALDH1A1TRPV6PGR | |
| SCHEMBL3543093 | 0.80 | MAPT (0.63) | NAMPTSLC18A3ALDH1A1TDP1MAPT | |
| SCHEMBL9351306 | 0.80 | SLC18A3 (0.46) | NAMPTSLC18A3ALDH1A1TRPV6PGR | |
| SCHEMBL3543089 | 0.80 | MAPT (0.63) | NAMPTSLC18A3ALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272580-B1 | Liquidcrystalline cyclohexylbenzene derivatives their manufacturing and novel nematic admixtures containing same | WOJSKOWA AKAD TECH (PL) | 1994-08-17 | — | — | EP | disclosed |
| EP-0272580-A2 | Liquidcrystalline cyclohexylbenzene derivatives their manufacturing and novel nematic admixtures containing same | Wojskowa Akademia Techniczna im. Jaroslawa Dabrowskiego (PL) | 1988-06-29 | — | — | EP | disclosed |