Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9342878 | 1.00 | PTPN2 (0.49) | PTPN2PTPN1PTPN6CHRM3ESR1 | |
| SCHEMBL9876082 | 0.98 | PTPN2 (0.50) | PTPN2PTPN1PTPN6CHRM3ESR1 | |
| SCHEMBL9344511 | 0.90 | TSHR (0.42) | PTPN2PTPN1PTPN6CHRM3ESR1 | |
| SCHEMBL9343512 | 0.90 | TSHR (0.42) | PTPN2PTPN1PTPN6CHRM3ESR1 | |
| SCHEMBL9347065 | 0.89 | L3MBTL1 (0.44) | PTPN2PTPN1PTPN6CHRM3ESR1 | |
| SCHEMBL9344500 | 0.88 | PTPN2 (0.44) | PTPN2PTPN1PTPN6CHRM3HRH3 | |
| SCHEMBL18911060 | 0.84 | ESR1 (0.39) | PTPN2PTPN1PTPN6CHRM3ESR1 | |
| SCHEMBL9343529 | 0.83 | PTPN2 (0.42) | PTPN2PTPN1PTPN6CHRM3ESR1 | |
| SCHEMBL9347033 | 0.82 | TSHR (0.58) | PTPN1CHRM3CHRM2CHRM1SLC6A2 | |
| SCHEMBL18905376 | 0.82 | ESR1 (0.37) | PTPN2PTPN1PTPN6CHRM3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328643-B1 | (alpha)-HYDROPEROXYISOPROPYLPHENYL COMPOUNDS AND PROCESS FOR THEIR PREPARATION | TERUMO CORP (JP) | 1994-07-06 | — | — | EP | disclosed |
| US-5043142-A | Measuring peroxide-active substances | TERUMO KABUSHIKI KAISHA (JP) | 1991-08-27 | — | — | US | disclosed |