Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL9342563 | 0.80 | TDP1 (0.43) | TDP1SMN1; SMN2MAPTPLA2G1BATG4B | |
| Ether SCHEMBL9343517 | 0.75 | MEN1 (0.41) | TDP1SMN1; SMN2MAPTALDH1A1KMT2A | |
| Ether SCHEMBL9342827 | 0.74 | TDP1 (0.40) | TDP1SMN1; SMN2MAPTPLA2G1BATG4B | |
| Ether SCHEMBL11171585 | 0.70 | TSHR (0.41) | SMN1; SMN2MAPTALDH1A1HPGDKMT2A | |
| Ether SCHEMBL11164208 | 0.70 | TSHR (0.41) | MAPTALDH1A1HPGDKMT2AMEN1 | |
| Ether SCHEMBL9343384 | 0.70 | TDP1 (0.46) | TDP1SMN1; SMN2MAPTPLA2G1BATG4B | |
| SCHEMBL9342797 | 0.69 | TDP1 (0.70) | TDP1SMN1; SMN2MAPTPLA2G1BATG4B | |
| SCHEMBL6552076 | 0.68 | TDP1 (0.64) | TDP1SMN1; SMN2MAPTPLA2G1BATG4B | |
| Ether SCHEMBL11350608 | 0.67 | MEN1 (0.42) | TDP1SMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL25285852 | 0.67 | KDM4E (0.53) | TDP1SMN1; SMN2MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304531-A | Preemergent, postemergent, controls weed growth 2-chloro-4-trifluoromethyl-3' (1-(carboethoxy) ethoxycarbonyl)-4-nitrodiphenyl ether | BASF CORPORATION | 1994-04-19 | — | — | US | disclosed |