SCHEMBL9347679

SCHEMBL9347679

CCCCC[C@H]1CO[C@H](c2cc(F)c(C)c(F)c2F)OC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.31
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9352059 0.99 ALDH1A1 (0.36) ALDH1A1CYP1A2GRM2
SCHEMBL9352026 0.96
SCHEMBL9349118 0.90
SCHEMBL9347981 0.84
SCHEMBL9347881 0.78 MEN1 (0.36) CYP1A2
SCHEMBL9503692 0.77 ALDH1A1 (0.37) ALDH1A1CYP1A2GRM2
SCHEMBL9347694 0.77 MEN1 (0.36) CYP1A2
SCHEMBL9347767 0.77 MAPT (0.37) CYP1A2GRM2
SCHEMBL9347753 0.77 MAPT (0.37) CYP1A2GRM2
SCHEMBL9763985 0.76 ALDH1A1 (0.40) ALDH1A1CYP1A2GRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5318721-A Nematic liquid-crystalline phases MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-06-07 US disclosed
US-4871469-A TRIFLUOROTOLUENE DERIVATIVES BESCRANKTER HAFTUNG (DE) 1989-10-03 US disclosed