Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347804 | 0.86 | NR1H2 (0.49) | KMT2AL3MBTL1NR1H2KDM4ECYP3A4 | |
| SCHEMBL6739313 | 0.85 | KMT2A (0.48) | KMT2AL3MBTL1ACENR1H2KDM4E | |
| SCHEMBL6743027 | 0.83 | KMT2A (0.48) | KMT2AL3MBTL1ACEGPR119STS | |
| SCHEMBL9347397 | 0.82 | KMT2A (0.52) | KMT2AL3MBTL1ACEGPR119STS | |
| SCHEMBL12480874 | 0.77 | GRM6 (0.43) | KMT2AACEMEN1 | |
| SCHEMBL9973492 | 0.77 | KMT2A (0.47) | KMT2AL3MBTL1GPR119STSKDM4E | |
| SCHEMBL4710677 | 0.77 | GRM6 (0.49) | KMT2AL3MBTL1ACEMEN1ALDH1A1 | |
| SCHEMBL4710674 | 0.77 | GRM6 (0.49) | KMT2AL3MBTL1ACEMEN1ALDH1A1 | |
| SCHEMBL29142190 | 0.77 | GRM6 (0.49) | KMT2AL3MBTL1ACEMEN1ALDH1A1 | |
| SCHEMBL27089262 | 0.77 | GRM6 (0.49) | KMT2AL3MBTL1ACEMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342963-A | Optically active pyrrolidine derivative | AJINOMOTO CO., INC. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0513398-A1 | INTERMEDIATE FOR SYNTHESIS OF CARBAPENEM AND PRODUCTION OF SAID INTERMEDIATE | Ajinomoto Co., Inc. (JP) | 1992-11-19 | — | — | EP | disclosed |