Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419826 | 0.90 | KMT2A (0.53) | KMT2AL3MBTL1ACECYP3A4KDM4E | |
| SCHEMBL9356309 | 0.89 | KMT2A (0.56) | KMT2AL3MBTL1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL9352224 | 0.89 | KMT2A (0.56) | KMT2AL3MBTL1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL6743027 | 0.85 | KMT2A (0.48) | KMT2AL3MBTL1ACECYP3A4KDM4E | |
| SCHEMBL23043376 | 0.85 | FKBP1A (0.53) | KMT2ACYP3A4KDM4EALDH1A1FKBP1A | |
| SCHEMBL9347282 | 0.85 | FKBP1A (0.53) | KMT2ACYP3A4KDM4EALDH1A1FKBP1A | |
| SCHEMBL4710677 | 0.84 | GRM6 (0.49) | KMT2AL3MBTL1ACEALDH1A1GRM6 | |
| SCHEMBL4710674 | 0.84 | GRM6 (0.49) | KMT2AL3MBTL1ACEALDH1A1GRM6 | |
| SCHEMBL29142190 | 0.84 | GRM6 (0.49) | KMT2AL3MBTL1ACEALDH1A1GRM6 | |
| SCHEMBL27089432 | 0.84 | GRM6 (0.49) | KMT2AL3MBTL1ACEALDH1A1GRM6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5342963-A | Optically active pyrrolidine derivative | AJINOMOTO CO., INC. (JP) | 1994-08-30 | — | — | US | disclosed |
| EP-0513398-A1 | INTERMEDIATE FOR SYNTHESIS OF CARBAPENEM AND PRODUCTION OF SAID INTERMEDIATE | Ajinomoto Co., Inc. (JP) | 1992-11-19 | — | — | EP | disclosed |