Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.35 |
| ▸ | CBS | P35520 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CD69 | Q07108 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1736365 | 0.81 | TSHR (0.35) | TSHRCTHCBSTHPOSMN1; SMN2 | |
| SCHEMBL15677656 | 0.80 | — | — | |
| SCHEMBL20002894 | 0.79 | — | — | |
| SCHEMBL10202772 | 0.76 | TSHR (0.35) | TSHRCTHCBSTHPOSMN1; SMN2 | |
| SCHEMBL31681398 | 0.75 | TSHR (0.38) | TSHRCTHCBSTHPOSMN1; SMN2 | |
| SCHEMBL11669967 | 0.75 | TSHR (0.38) | TSHRCTHCBSTHPOSMN1; SMN2 | |
| SCHEMBL18840321 | 0.74 | TSHR (0.41) | TSHRCTHCBSTHPOSMN1; SMN2 | |
| SCHEMBL1118445 | 0.74 | — | — | |
| SCHEMBL431399 | 0.74 | — | — | |
| SCHEMBL7682659 | 0.74 | TSHR (0.41) | TSHRCTHCBSTHPOSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362477-A | 19F magnetic resonance imaging agents which include a nitroxide moiety | MALLINCKRODT MEDICAL, INC. (US) | 1994-11-08 | — | — | US | disclosed |