Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.89 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.89 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL4541130 | 1.00 | ALDH1A1 (0.89) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| Ethylene Glycol SCHEMBL28206604 | 0.95 | ALDH1A1 (0.86) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| Methyl Alcohol SCHEMBL7346314 | 0.94 | ALDH1A1 (0.92) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL12977796 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL10482100 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL6377533 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL6376906 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL9501546 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL260571 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 | |
| SCHEMBL262010 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TDP1SMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349787-B1 | An additive to metal cold rolling oil | DAI ICHI KOGYO SEIYAKU CO LTD (JP) | 1994-08-31 | — | — | EP | disclosed |
| EP-0349787-A2 | An additive to metal cold rolling oil | DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |