Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HBB | P68871 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288534 | 0.85 | TP53 (0.41) | TP53L3MBTL1GLAHSD17B10DGAT1 | |
| SCHEMBL10564928 | 0.80 | KDM4E (0.44) | KMT2ADGAT1NOTUMMAPTHTT | |
| SCHEMBL10559290 | 0.80 | KDM4E (0.45) | TP53KMT2ADGAT1MAPTHTT | |
| SCHEMBL10562759 | 0.80 | KDM4E (0.53) | FFAR1MAPTHTTHPGDPOLB | |
| SCHEMBL5142502 | 0.76 | MAPT (0.38) | HSD17B10TDP1MITFKMT2ANOTUM | |
| SCHEMBL7605648 | 0.75 | METAP1 (0.56) | TDP1MAPTALDH1A1HPGD | |
| SCHEMBL4950715 | 0.74 | PTGIR (0.45) | TDP1KMT2AMAPTHTTMAOB | |
| SCHEMBL7296956 | 0.74 | HTT (0.37) | TP53L3MBTL1DGAT1HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10916080 | 0.74 | METAP1 (0.57) | TDP1MAPTALDH1A1HPGD | |
| SCHEMBL68883 | 0.73 | HPGD (0.37) | TDP1KMT2ANOTUMMAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292768-A | Compound effective as cerebral insufficiency improver | SUNTORY LIMITED (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5288752-A | Brain disorders | SUNTORY LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
| EP-0322248-B1 | COMPOUNDS EFFECTIVE AGAINST CEREBRAL INSUFFICIENCY | SUNTORY LIMITED (JP) | 1993-08-04 | — | — | EP | disclosed |
| US-5179092-A | Cognition activators | SUNTORY LIMITED (JP) | 1993-01-12 | — | — | US | disclosed |
| US-5057514-A | Compounds effective as cerebral schemia treating agents | SUNTORY LIMITED (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0322248-A2 | Compounds effective against cerebral insufficiency | SUNTORY LIMITED (JP) | 1989-06-28 | — | — | EP | disclosed |
| US-4843075-A | ANXIOLYTIC | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0252990-A1 | BENZOTHIOPYRANO(4,3-C)PYRIDAZINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1988-01-20 | — | — | EP | disclosed |