Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.30 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10544918 | 0.84 | GAA (0.40) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL9331492 | 0.84 | GAA (0.33) | GAAL3MBTL1POLB | |
| SCHEMBL10404397 | 0.84 | GAA (0.36) | GAAL3MBTL1POLBSMN1; SMN2 | |
| SCHEMBL10546566 | 0.83 | GAA (0.40) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL10546548 | 0.81 | GAA (0.34) | GAAL3MBTL1POLB | |
| SCHEMBL10544966 | 0.80 | GAA (0.37) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL10720122 | 0.80 | GAA (0.37) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL10403345 | 0.80 | GAA (0.37) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL10546522 | 0.80 | GAA (0.37) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 | |
| SCHEMBL10543143 | 0.80 | GAA (0.37) | GAAL3MBTL1POLBSMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |