Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.51 |
| ▸ | MME | P08473 | 3/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325571 | 0.88 | SLC1A3 (0.45) | ECE1MMEACE2 | |
| SCHEMBL6843865 | 0.82 | ACP3 (0.42) | — | |
| SCHEMBL7328790 | 0.81 | SLC1A3 (0.44) | ECE1MMEACE2 | |
| SCHEMBL7367235 | 0.81 | LTA4H (0.38) | MMEACE2 | |
| SCHEMBL6257526 | 0.80 | LTA4H (0.40) | MMEACE2 | |
| SCHEMBL7367102 | 0.80 | LTA4H (0.37) | MMEACE2 | |
| SCHEMBL7364027 | 0.79 | MME (0.56) | ECE1MMEACE2CTSKCAPN1 | |
| SCHEMBL7386283 | 0.79 | LTA4H (0.37) | MMEACE2 | |
| SCHEMBL6412346 | 0.79 | CPA1 (0.45) | ECE1ACE2 | |
| SCHEMBL7368486 | 0.79 | LTA4H (0.36) | MMEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612324-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1994-08-31 | — | — | EP | disclosed |