Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545026 | 0.71 | PIK3CD (0.30) | — | |
| SCHEMBL7069375 | 0.69 | — | — | |
| SCHEMBL9782969 | 0.68 | OPRM1 (0.33) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL9326406 | 0.68 | OPRM1 (0.32) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL10486755 | 0.67 | — | — | |
| SCHEMBL9329350 | 0.66 | OPRM1 (0.34) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL17485954 | 0.65 | KMT2A (0.46) | — | |
| SCHEMBL9782970 | 0.65 | — | — | |
| SCHEMBL14283165 | 0.64 | — | — | |
| SCHEMBL9326415 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258598-B1 | N-(substituted-1-piperazinealkyl)-alpha-(3,5-di-alkyl-4-hydroxyphenyl)-alpha,alpha-dialkyl acetamides | GOODRICH CO B F (US) | 1994-09-07 | — | — | EP | disclosed |
| EP-0253010-B1 | N-(SUBSTITUTED CYCLIC ALKYLENEIMINE)-ALPHA-(3,5-DI-ALKYL-4-HYDROXY-PHENYL)-ALPHA, ALPHA-DIALKYL ACETAMIDES | The B.F. GOODRICH Company (US) | 1992-12-02 | — | — | EP | disclosed |