Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 8/20 | 0.74 |
| ▸ | MAOA | P21397 | 5/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glyfoline SCHEMBL31285722 | 1.00 | CTSV (0.74) | CTSVMAOAKDM1ACYP19A1PTGS2 | |
| Citibrasine SCHEMBL9352197 | 0.85 | CTSV (1.00) | CTSVMAOAKDM1ACYP19A1KDM4E | |
| SCHEMBL9348539 | 0.85 | CTSV (0.68) | CTSVMAOAKDM1ACYP19A1NQO2 | |
| SCHEMBL31384423 | 0.84 | CTSV (0.76) | CTSVMAOAKDM1ACYP19A1PTGS2 | |
| SCHEMBL29877319 | 0.81 | CTSV (0.53) | CTSVMAOAKDM1ACYP19A1PTGS2 | |
| SCHEMBL9348595 | 0.78 | CTSV (0.60) | CTSVMAOAKDM1ACYP19A1KDM4E | |
| SCHEMBL9349831 | 0.78 | CTSV (0.58) | CTSVKDM1ACYP19A1NQO2ALDH1A1 | |
| SCHEMBL9348590 | 0.77 | CTSV (0.57) | CTSVKDM1ACYP19A1NQO2ALDH1A1 | |
| SCHEMBL9352227 | 0.76 | CTSV (0.60) | CTSVMAOAKDM1ACYP19A1KDM4E | |
| Citpressine Ii SCHEMBL29711402 | 0.75 | CTSV (0.52) | CTSVMAOAKDM1AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016509-A1 | MULTISUBSTITUTED 1-HYDROXY-9-ACRIDONES WITH ANTICANCER ACTIVITY | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-10-01 | — | — | WO | claimed |
| US-5296602-A | Condensing substituted ortho-halo- or ortho-aminobenzoic acid with meta-halo- or meta-aminoanisole, cyclizing, N-alkylating, de-O-methylating | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1994-03-22 | — | — | US | disclosed |
| WO-1992016509-A1 | MULTISUBSTITUTED 1-HYDROXY-9-ACRIDONES WITH ANTICANCER ACTIVITY | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-10-01 | — | — | WO | disclosed |