SCHEMBL9348557

SCHEMBL9348557

CC(=O)Nc1n[nH]c2ccc(C(=O)c3ccccc3)cc12

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.51
CDK7 P50613 5/20 0.50
GSK3A P49840 2/20 0.50
GSK3B P49841 2/20 0.50
KDR P35968 2/20 0.50
ALDH1A1 P00352 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
JAK2 O60674 2/20 0.48
JAK1 P23458 1/20 0.48
MAPK1 P28482 4/20 0.47
CDK2 P24941 3/20 0.47
PLK4 O00444 1/20 0.47
AURKA O14965 1/20 0.47
MAPK13 O15264 1/20 0.47
DAPK3 O43293 1/20 0.47
PRKCG P05129 1/20 0.47
CDK1 P06493 1/20 0.47
RPS6KB1 P23443 1/20 0.47
TYK2 P29597 1/20 0.47
CLK2 P49760 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18812677 0.78 CDK7 (0.63) DYRK1ACDK7KDRJAK2JAK1
SCHEMBL628880 0.78 DYRK1A (0.63) DYRK1AGSK3AGSK3BJAK2MAPK1
SCHEMBL3511548 0.77 JAK2 (0.66) KDRALDH1A1L3MBTL1JAK2JAK1
SCHEMBL18932050 0.76 CDK7 (0.49) CDK7GSK3AGSK3BJAK2JAK1
SCHEMBL627302 0.76 GSK3B (0.60) DYRK1AGSK3AGSK3BALDH1A1JAK2
SCHEMBL18828988 0.75 CDK7 (0.48) CDK7GSK3AGSK3BJAK2JAK1
SCHEMBL18812678 0.75 CDK7 (0.48) CDK7GSK3AGSK3BJAK2JAK1
SCHEMBL18828989 0.75 CDK7 (0.48) CDK7GSK3AGSK3BJAK2JAK1
SCHEMBL18932071 0.75 CDK7 (0.49) CDK7GSK3AGSK3BALDH1A1JAK2
SCHEMBL18812687 0.75 CDK7 (0.49) CDK7GSK3AGSK3BALDH1A1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238271-B1 Silver halide photographic material and method of processing the same KONISHIROKU PHOTO IND (JP) 1994-08-10 EP disclosed
US-4897340-A RAPIDLY AUTOMATIC PROCESSABLE FILMS HAVING A HYDROPHILIC COLLOIDAL PROTECTIVE LAYER AND A LAYER CONTAINING CORE/SHELL OR TUBULAR GRAINS OF SILVER HALIDE; X-RAY FILMS; WEAR RESISTANCE; ANTISOILANTS KONICA CORPORATION (JP) 1990-01-30 US disclosed
EP-0316864-A2 Silver halide photographic light-sensitive material and processing method KONICA CORPORATION (JP) 1989-05-24 EP disclosed
EP-0238271-A2 Silver halide photographic material and method of processing the same KONICA CORPORATION (JP) 1987-09-23 EP disclosed
EP-0060118-B1 STABLE PHOTOGRAPHIC DEVELOPING SOLUTION CONTAINING AN INDAZOLE ANTIFOGGANT AND A LIGNOSULFONATE EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-02-13 EP disclosed
EP-0060118-A1 Stable photographic developing solution containing an indazole antifoggant and a lignosulfonate EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-09-15 EP disclosed
US-4323642-A Stable photographic developers containing an indazole antifoggant and a lignosulfonate EASTMAN KODAK COMPANY (US) 1982-04-06 US disclosed