SCHEMBL9348587

SCHEMBL9348587

CC1CCC(c2ccc(Oc3cccc(N)c3)cc2)(c2ccc(Oc3cccc(N)c3)cc2)CC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.50
ALDH1A1 P00352 5/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MITF O75030 1/20 0.44
GAA P10253 1/20 0.44
GFER P55789 1/20 0.44
NLRP1 Q9C000 1/20 0.44
NOD2 Q9HC29 1/20 0.44
ATM Q13315 1/20 0.43
LTA4H P09960 1/20 0.41
CYP3A4 P08684 2/20 0.40
POLB P06746 1/20 0.39
HSP90AA1 P07900 1/20 0.39
TP53 P04637 1/20 0.37
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
NLRP3 Q96P20 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9348875 0.92 MAOB (0.45) MAOBALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL9348631 0.92 MAOB (0.45) MAOBALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL9348636 0.92 MAOB (0.45) MAOBALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL9350115 0.86 MAOB (0.47) MAOBALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL1305916 0.85 ALDH1A1 (0.47) MAOBALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL9349988 0.84 MAOB (0.47) MAOBALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL9349892 0.83 MAOB (0.44) MAOBALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL9348867 0.83 MAPT (0.42) MAOBALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL9348855 0.82 MAOB (0.43) MAOBALDH1A1SMN1; SMN2MAPTMEN1
SCHEMBL9348847 0.82 MAOB (0.43) MAOBALDH1A1SMN1; SMN2MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0389092-B1 Liquid crystal-aligning coating and liquid crystal element CHISSO CORP (JP) 1994-09-07 EP disclosed
US-5152918-A Cyclohexyl aromatic polyimides; controlling pretilt angle CHISSO CORPORATION (JP) 1992-10-06 US disclosed
EP-0389092-A1 Liquid crystal-aligning coating and liquid crystal element CHISSO CORPORATION (JP) 1990-09-26 EP disclosed