Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.43 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 4/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9348776 | 1.00 | FOLH1 (0.43) | FOLH1NAALAD2RIMKLABACE1NOD1 | |
| SCHEMBL29351135 | 0.89 | GNPAT (0.45) | FOLH1NAALAD2RIMKLABACE1NOD1 | |
| SCHEMBL30930177 | 0.89 | GLO1 (0.42) | FOLH1NAALAD2RIMKLABACE1NOD1 | |
| SCHEMBL29352968 | 0.88 | FOLH1 (0.41) | FOLH1NAALAD2RIMKLANOD1GLO1 | |
| SCHEMBL31332141 | 0.88 | FOLH1 (0.41) | FOLH1NAALAD2RIMKLANOD1GLO1 | |
| SCHEMBL30590545 | 0.86 | FOLH1 (0.50) | FOLH1NAALAD2RIMKLABACE1NOD1 | |
| SCHEMBL30906691 | 0.85 | BACE1 (0.46) | FOLH1BACE1CTSD | |
| SCHEMBL29630420 | 0.84 | BACE1 (0.52) | FOLH1NAALAD2RIMKLABACE1CTSD | |
| SCHEMBL29605022 | 0.83 | BACE1 (0.49) | BACE1CTSD | |
| SCHEMBL9622060 | 0.83 | FOLH1 (0.56) | FOLH1NAALAD2RIMKLANOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376356-A | Imaging tissue sites of inflammation | NEORX CORPORATION (US) | 1994-12-27 | — | — | US | disclosed |
| US-5100378-A | Lymph cells, infusion and blocking agents | NEORX CORPORATION (US) | 1992-03-31 | — | — | US | disclosed |
| EP-0463116-A4 | IMAGING TISSUE SITES OF INFLAMMATION | — | 1992-02-19 | — | — | EP | disclosed |
| EP-0463116-A1 | IMAGING TISSUE SITES OF INFLAMMATION | NEORX CORPORATION (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4986979-A | Imaging tissue sites of inflammation | NEORX CORPORATION | 1991-01-22 | — | — | US | disclosed |
| WO-1990010463-A1 | IMAGING TISSUE SITES OF INFLAMMATION | NEORX CORPORATION (US) | 1990-09-20 | — | — | WO | disclosed |