Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 16/20 | 0.64 |
| ▸ | RAB9A | P51151 | 16/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.50 |
| ▸ | RELA | Q04206 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28255422 | 0.86 | RAB9A (0.82) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL29669763 | 0.86 | RAB9A (0.82) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7191660 | 0.80 | EPHX1 (0.64) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30499685 | 0.80 | EPHX1 (0.64) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7603173 | 0.78 | KMT2A (0.52) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL30499670 | 0.77 | KMT2A (0.67) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9352522 | 0.77 | KMT2A (0.67) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| Dichlorbenzuron SCHEMBL3663126 | 0.77 | CNR1 (0.54) | NPC1RAB9AMEN1KMT2AGAA | |
| SCHEMBL9348738 | 0.77 | MAPT (0.48) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL7605671 | 0.77 | SLC2A1 (0.50) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142064-A | Larvicides has benzoyl or thiobenzoyl group | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-08-25 | — | — | US | claimed |
| US-5342958-A | Insecticides | SOLVAY DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1994-08-30 | — | — | US | disclosed |
| US-5245071-A | Insecticides | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1993-09-14 | — | — | US | disclosed |
| US-5142064-A | Larvicides has benzoyl or thiobenzoyl group | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1992-08-25 | — | — | US | disclosed |
| US-4920135-A | NONPHYTOTOXIC, INTERFERE WITH METAMORPHOSIS | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-04-24 | — | — | US | disclosed |
| US-4833151-A | INTERFERES WITH METAMORPHOSES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1989-05-23 | — | — | US | disclosed |
| US-4607044-A | Insecticidal use of ureas and thioureas | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-08-19 | — | — | US | disclosed |
| US-4166124-A | IMIDAZOLE OR PYRIMIDINE RINGS | U.S. PHILIPS CORPORATION (US) | 1979-08-28 | — | — | US | disclosed |
| US-4013717-A | BENZOYL PHENYL UREA DERIVATIVES HAVING INSECTICIDAL ACTIVITIES | U.S. PHILIPS CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |
| US-3989842-A | Certain substituted benzoyl urea insecticides | U.S. PHILIPS CORPORATION (US) | 1976-11-02 | — | — | US | disclosed |
| US-3933908-A | INSECTICIDE | U.S. PHILIPS CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |