Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346229 | 0.96 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTTDP1CYP2C19 | |
| SCHEMBL9346137 | 0.92 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAPTTDP1CYP2C19 | |
| SCHEMBL988373 | 0.83 | TP53 (0.50) | ALDH1A1MAPTTDP1KDM4ECYP3A4 | |
| SCHEMBL9346196 | 0.82 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTTDP1CYP2C19 | |
| SCHEMBL9350315 | 0.82 | ESR1 (0.48) | ALDH1A1L3MBTL1MAPTTDP1CYP2C19 | |
| SCHEMBL9346655 | 0.82 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTTDP1CYP2C19 | |
| SCHEMBL28291474 | 0.78 | TP53 (0.50) | ALDH1A1MAPTTDP1KDM4ECYP3A4 | |
| SCHEMBL23264336 | 0.76 | TP53 (0.62) | ALDH1A1L3MBTL1MAPTTDP1CYP2C19 | |
| SCHEMBL10062461 | 0.76 | TP53 (0.62) | ALDH1A1L3MBTL1MAPTTDP1CYP2C19 | |
| SCHEMBL2632329 | 0.76 | TP53 (0.62) | ALDH1A1L3MBTL1MAPTTDP1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290963-A | Silane containing triarylamines, prepared from Grignard reagents, electrography | KAO CORPORATION (JP) | 1994-03-01 | — | — | US | disclosed |
| EP-0457212-A1 | Novel organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it | Kao Corporation (JP) | 1991-11-21 | — | — | EP | disclosed |