Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 16/20 | 0.74 |
| ▸ | STAT6 | P42226 | 2/20 | 0.74 |
| ▸ | DPP4 | P27487 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.74 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.74 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.74 |
| ▸ | GAPDH | P04406 | 1/20 | 0.74 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.74 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.74 |
| ▸ | PI4KA | P42356 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.74 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.74 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.74 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9347373 | 1.00 | SLC29A1 (0.74) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL8500982 | 0.91 | SLC29A1 (0.78) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL19488384 | 0.89 | SMN1; SMN2 (0.77) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL240981 | 0.89 | SMN1; SMN2 (0.77) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL672036 | 0.89 | SMN1; SMN2 (0.77) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL672035 | 0.89 | SMN1; SMN2 (0.77) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL30089484 | 0.89 | SMN1; SMN2 (0.77) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL7134319 | 0.89 | SMN1; SMN2 (0.77) | SLC29A1STAT6DPP4MEN1SLC28A1 | |
| SCHEMBL15623875 | 0.87 | SLC29A1 (0.75) | SLC29A1STAT6 | |
| SCHEMBL3675456 | 0.87 | SLC29A1 (0.75) | SLC29A1STAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353268-B1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INST (US) | 1994-08-10 | — | — | EP | disclosed |
| US-5026836-A | Antitumor agents | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0353268-A4 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS. | NUCLEIC ACID RES INST (US) | 1990-05-14 | — | — | EP | disclosed |
| EP-0353268-A1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS. | NUCLEIC ACID RESEARCH INST (US) | 1990-02-07 | — | — | EP | disclosed |
| WO-1989005817-A1 | ANTITUMOR 6-SULFENAMIDE, 6-SULFINAMIDE AND 6-SULFONAMIDE PURINES, PURINE NUCLEOSIDES, PURINE NUCLEOTIDES AND RELATED COMPOUNDS | NUCLEIC ACID RESEARCH INSTITUTE (US) | 1989-06-29 | — | — | WO | disclosed |