SCHEMBL935058

SCHEMBL935058

Cc1ccc(N(C)C(=O)O)c(C)c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
TP53 P04637 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
SMN1; SMN2 Q16637 5/20 0.39
HTT P42858 2/20 0.39
CSNK2A1 P68400 1/20 0.38
KDM4E B2RXH2 2/20 0.38
NFE2L2 Q16236 1/20 0.37
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.36
NPC1 O15118 1/20 0.36
CASP3 P42574 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30937126 0.84 KDM4E (0.40) MEN1KMT2ATP53TDP1SMN1; SMN2
SCHEMBL11184627 0.84 POLB (0.48) MEN1KMT2ATP53SMN1; SMN2CSNK2A1
SCHEMBL6836569 0.84 CSNK2A1 (0.47) MEN1KMT2ATP53TDP1SMN1; SMN2
SCHEMBL13043265 0.84 FSCN1 (0.50) MEN1KMT2ATP53TDP1SMN1; SMN2
SCHEMBL10494557 0.82 MAPT (0.38) MEN1KMT2ATP53SMN1; SMN2CSNK2A1
SCHEMBL10944139 0.82 TP53 (0.39) MEN1KMT2ATP53TDP1SMN1; SMN2
SCHEMBL1018391 0.81 PDE10A (0.44) MEN1KMT2ATDP1KDM4EMAPT
SCHEMBL20660751 0.81 ALDH1A1 (0.39) MEN1KMT2AHTTKDM4EMAPT
SCHEMBL22583707 0.81 PDK2 (0.45) MEN1KMT2ACSNK2A1
SCHEMBL28706175 0.81 CSNK2A1 (0.53) MEN1KMT2ASMN1; SMN2CSNK2A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090023667-A1 Composition For Preventing Harmful Organisms MITSUI CHEMICALS, INC. (JP) 2009-01-22 US claimed
EP-2003968-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PRODUCTS, SO INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF Leschot Sanhueza, Andres Antonio (CL) 2008-12-24 EP claimed
EP-1872658-A1 PESTICIDAL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-01-02 EP claimed
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof NAPPA ALVARO O 2007-10-04 US claimed
WO-2007110801-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PORDUCTS, INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF LESCHOT SANHUEZA ANDRES ANTONI (CL) 2007-10-04 WO claimed
US-20050171064-A1 Insecticide for Acarina comprising synergistic mixture including a 4-nitroimino or 4-cyanoimino 1,3,5-oxadiazine such as 5-(2-chlorothiazol-5-ylmethyl)-3-methyl-4-nitroimino-perhydro-1,3,5-oxadiazine and another pesticide such as pirimicarb SENN ROBERT (CH) 2005-08-04 US claimed
CN-110325040-B Plant disease control composition and method for controlling plant disease using same 三井化学AGRO株式会社 2022-04-05 CN disclosed
EP-3710453-A1 SINGLE ENANTIOMER ANTIPARASITIC COMPOUNDS Avista Pharma Solutions, Inc. (US) 2020-09-23 EP disclosed
CN-110325040-A Plant disease control composition and apply its plant disease the method for control 三井化学AGRO株式会社 2019-10-11 CN disclosed
WO-2018009751-A1 ANTIPARASITIC COMPOUNDS AVISTA PHARMA SOLUTIONS, INC. (US) 2018-01-11 WO disclosed
WO-2017201134-A1 SYNTHETIC PROCESS AND NOVEL INTERMEDIATES AVISTA PHARMA SOLUTIONS, INC. (US) 2017-11-23 WO disclosed
EP-3245209-A1 ANTIPARASITIC COMPOUNDS Avista Pharma Solutions, Inc. (US) 2017-11-22 EP disclosed
WO-2016183173-A1 ANTIPARASITIC COMPOUNDS Avista Pharma Solutions (US) 2016-11-17 WO disclosed
CN-101160052-A Pesticidal composition MITSUI CHEMICALS INC (JP) 2008-04-09 CN disclosed
EP-1872658-A1 PESTICIDAL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-01-02 EP disclosed
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof NAPPA ALVARO O 2007-10-04 US disclosed
WO-2007110801-A2 COMPOSITIONS AND METHODS TO ADD VALUE TO PLANT PORDUCTS, INCREASING THE COMMERCIAL QUALITY, RESISTANCE TO EXTERNAL FACTORS AND POLYPHENOL CONTENT THEREOF LESCHOT SANHUEZA ANDRES ANTONI (CL) 2007-10-04 WO disclosed
EP-1165527-A1 PESTICIDAL ENANTIOMER-PURE 2,4-DISUBSTITUTED OXAZOLINES Novartis AG (CH) 2002-01-02 EP disclosed
WO-2000058291-A1 PESTICIDAL ENANTIOMER-PURE 2,4-DISUBSTITUTED OXAZOLINES NOVARTIS AG (CH) 2000-10-05 WO disclosed
US-4381936-A CARBAMATE STABILIZER WITH A THIOCARBAMATE STAUFFER CHEMICAL COMPANY (US) 1983-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050171064-A1 Insecticide for Acarina comprising synergistic mixture including a 4-nitroimino or 4-cyanoimino 1,3,5-oxadiazine such as 5-(2-chlorothiazol-5-ylmethyl)-3-methyl-4-nitroimino-perhydro-1,3,5-oxadiazine and another pesticide such as pirimicarb CNPY2, CBR3, CNPY3 MEN1 4702/4885KMT2A 828/4885TP53 2505/4885
US-20070232495-A1 Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof C5, PNN, NQO1 MEN1 3272/4885KMT2A 3257/4885TP53 1790/4885
US-20090023667-A1 Composition For Preventing Harmful Organisms DDT, CBR3, AHR MEN1 2918/4885KMT2A 1247/4885TP53 4445/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.