Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9346988 | 0.82 | KDM4E (0.37) | ATML3MBTL1KDM4ECA1CA2 | |
| SCHEMBL9347250 | 0.79 | KDM4E (0.36) | ATML3MBTL1KDM4ECA1CA2 | |
| SCHEMBL7613158 | 0.79 | CA1 (0.37) | ATML3MBTL1KDM4ECA1CA2 | |
| SCHEMBL7607426 | 0.79 | CA1 (0.37) | ATML3MBTL1KDM4ECA1CA2 | |
| SCHEMBL9347275 | 0.78 | KDM4E (0.35) | ATML3MBTL1KDM4ESCN10AALDH1A1 | |
| SCHEMBL26607 | 0.78 | CA1 (0.41) | ATML3MBTL1KDM4ECA1CA2 | |
| SCHEMBL29349873 | 0.78 | CA1 (0.41) | ATML3MBTL1KDM4ECA1CA2 | |
| SCHEMBL9347011 | 0.78 | CA1 (0.41) | ATML3MBTL1KDM4ECA1CA2 | |
| SCHEMBL9347000 | 0.77 | ATM (0.36) | ATML3MBTL1KDM4ECA1CA2 | |
| SCHEMBL9347279 | 0.77 | PGR (0.35) | ATML3MBTL1KDM4ECA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5298644-A | Aryl phosphinites | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-03-29 | — | — | US | disclosed |