Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10885468 | 0.90 | RAB9A (0.59) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL10493299 | 0.89 | RAB9A (0.54) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL10885461 | 0.89 | RAB9A (0.54) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL12289156 | 0.84 | RAB9A (0.51) | RAB9AHTTNPC1HTR2ATDP1 | |
| SCHEMBL21895729 | 0.83 | SRC (0.57) | TDP1L3MBTL1 | |
| SCHEMBL1581485 | 0.83 | SRC (0.57) | TDP1L3MBTL1 | |
| SCHEMBL6559779 | 0.83 | RAB9A (0.56) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL6772418 | 0.83 | RAB9A (0.53) | RAB9AMAPTHTTNPSR1NPC1 | |
| SCHEMBL10493215 | 0.83 | RAB9A (0.44) | RAB9AHTTHTR2ATDP1IDO1 | |
| SCHEMBL11310853 | 0.83 | RAB9A (0.48) | RAB9AMAPTHTTNPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300497-A | Broad spectrum antibiotics and bactericides; stable to beta-lactamase; effective against antibiotic-resistant bacteria | TOYAMA CHEMICAL CO., LTD. (JP) | 1994-04-05 | — | — | US | disclosed |
| US-5185330-A | Penicillins/ad/ | TOYAMA CHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| US-4801704-A | PENICILLINS | HOFFMAN-LA ROCHE INC. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0206000-A1 | (2,3)-Alpha-methylenepenam-3-carboxylic acids and derivatives thereof | F. HOFFMANN-LA ROCHE AG (CH) | 1986-12-30 | — | — | EP | disclosed |
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |
| US-3935193-A | ANTIBIOTICS | TOYO JOZO KABUSHIKI KAISHA (JA) | 1976-01-27 | — | — | US | disclosed |